diff --git a/CHANGELOG.md b/CHANGELOG.md
index 14f320353..f194c4c76 100644
--- a/CHANGELOG.md
+++ b/CHANGELOG.md
@@ -5,12 +5,15 @@ All notable changes to this project will be documented in this file.
 
 ## [13.2.0.1]
 ### Added
+- ESP32 I2C bus2 support to iAQ core driver (#19799)
 
 ### Breaking Changed
 
 ### Changed
+- Prepare I2C drivers for bus2 support
 
 ### Fixed
+- ESP32 I2C allow bus2 support when bus1 is not enabled
 
 ### Removed
 
diff --git a/RELEASENOTES.md b/RELEASENOTES.md
index 0d752bd8a..e6361ba1b 100644
--- a/RELEASENOTES.md
+++ b/RELEASENOTES.md
@@ -113,11 +113,13 @@ The latter links can be used for OTA upgrades too like ``OtaUrl https://ota.tasm
 ## Changelog v13.2.0.1
 ### Added
 - Experimental support for ESP32-C2 and ESP32-C6 using Arduino core v3
+- ESP32 I2C bus2 support to iAQ core driver [#19799](https://github.com/arendst/Tasmota/issues/19799)
 
 ### Breaking Changed
 
 ### Changed
 
 ### Fixed
+- ESP32 I2C allow bus2 support when bus1 is not enabled
 
 ### Removed
diff --git a/tasmota/tasmota_support/support_a_i2c.ino b/tasmota/tasmota_support/support_a_i2c.ino
index 32237d173..68b557a54 100644
--- a/tasmota/tasmota_support/support_a_i2c.ino
+++ b/tasmota/tasmota_support/support_a_i2c.ino
@@ -49,15 +49,25 @@ bool I2c2Begin(int sda, int scl, uint32_t frequency) {
 }
 #endif
 
+TwoWire& I2cGetWire(uint8_t bus = 0) {
+  if (!bus && TasmotaGlobal.i2c_enabled) {
+    return Wire;
+#ifdef ESP32
+  } else if (bus && TasmotaGlobal.i2c_enabled_2) {
+    return Wire1;
+#endif  // ESP32
+  } else {
+//    AddLog(LOG_LEVEL_ERROR, PSTR("I2C: bus%d not initialized"), bus +1);
+    return *(TwoWire*)nullptr;
+  }
+}
+
 bool I2cValidRead(uint8_t addr, uint8_t reg, uint8_t size, uint8_t bus = 0) {
   i2c_buffer = 0;
-#ifdef ESP32
-  if (bus && !TasmotaGlobal.i2c_enabled_2) { return false; }  // Error
-  TwoWire & myWire = (bus == 0) ? Wire : Wire1;
-#else
-  if (bus) { return false; }                              // Second I2c bus ESP32 only
-  TwoWire & myWire = Wire;
-#endif
+
+  TwoWire& myWire = I2cGetWire(bus);
+  if (&myWire == nullptr) { return false; }               // No valid I2c bus
+
   uint8_t retry = I2C_RETRY_COUNTER;
   bool status = false;
   while (!status && retry) {
@@ -147,13 +157,9 @@ int32_t I2cRead24(uint8_t addr, uint8_t reg, uint8_t bus = 0) {
 }
 
 bool I2cWrite(uint8_t addr, uint8_t reg, uint32_t val, uint8_t size, uint8_t bus = 0) {
-#ifdef ESP32
-  if (bus && !TasmotaGlobal.i2c_enabled_2) { return false; }  // Error
-  TwoWire & myWire = (bus == 0) ? Wire : Wire1;
-#else
-  if (bus) { return false; }  // Second I2c bus ESP32 only
-  TwoWire & myWire = Wire;
-#endif
+  TwoWire& myWire = I2cGetWire(bus);
+  if (&myWire == nullptr) { return false; }               // No valid I2c bus
+
   uint8_t x = I2C_RETRY_COUNTER;
   do {
     myWire.beginTransmission((uint8_t)addr);              // start transmission to device
@@ -176,13 +182,9 @@ bool I2cWrite16(uint8_t addr, uint8_t reg, uint32_t val, uint8_t bus = 0) {
 }
 
 bool I2cReadBuffer(uint8_t addr, uint8_t reg, uint8_t *reg_data, uint16_t len, uint8_t bus = 0) {
-#ifdef ESP32
-  if (bus && !TasmotaGlobal.i2c_enabled_2) { return true; }  // Error
-  TwoWire & myWire = (bus == 0) ? Wire : Wire1;
-#else
-  if (bus) { return true; }  // Second I2c bus ESP32 only
-  TwoWire & myWire = Wire;
-#endif
+  TwoWire& myWire = I2cGetWire(bus);
+  if (&myWire == nullptr) { return true; }               // No valid I2c bus
+
   myWire.beginTransmission((uint8_t)addr);
   myWire.write((uint8_t)reg);
   myWire.endTransmission();
@@ -197,13 +199,9 @@ bool I2cReadBuffer(uint8_t addr, uint8_t reg, uint8_t *reg_data, uint16_t len, u
 }
 
 int8_t I2cWriteBuffer(uint8_t addr, uint8_t reg, uint8_t *reg_data, uint16_t len, uint8_t bus = 0) {
-#ifdef ESP32
-  if (bus && !TasmotaGlobal.i2c_enabled_2) { return 1; }  // Error
-  TwoWire & myWire = (bus == 0) ? Wire : Wire1;
-#else
-  if (bus) { return 1; }  // Second I2c bus ESP32 only
-  TwoWire & myWire = Wire;
-#endif
+  TwoWire& myWire = I2cGetWire(bus);
+  if (&myWire == nullptr) { return 1; }                   // No valid I2c bus
+
   myWire.beginTransmission((uint8_t)addr);
   myWire.write((uint8_t)reg);
   while (len--) {
@@ -229,16 +227,14 @@ void I2cScan(uint8_t bus = 0) {
   // 3: received NACK on transmit of data
   // 4: other error
   // 5: timeout
-
+  TwoWire& myWire = I2cGetWire(bus);
+  if (&myWire == nullptr) { return; }  // No valid I2c bus
 #ifdef ESP32
-  if (bus && !TasmotaGlobal.i2c_enabled_2) { return; }
-  TwoWire & myWire = (bus == 0) ? Wire : Wire1;
   Response_P(PSTR("{\"" D_CMND_I2CSCAN "\":\"Device(s) found on bus%d at"), bus +1);
 #else
-  if (bus) { return; }  // Second I2c bus ESP32 only
-  TwoWire & myWire = Wire;
   Response_P(PSTR("{\"" D_CMND_I2CSCAN "\":\"Device(s) found at"));
 #endif
+
   uint8_t error = 0;
   uint8_t address = 0;
   uint8_t any = 0;
@@ -311,13 +307,9 @@ bool I2cActive(uint32_t addr, uint8_t bus = 0) {
 }
 
 bool I2cSetDevice(uint32_t addr, uint8_t bus = 0) {
-#ifdef ESP32
-  if (bus && !TasmotaGlobal.i2c_enabled_2) { return false; }  // If no second bus report as not present;
-  TwoWire & myWire = (bus == 0) ? Wire : Wire1;
-#else
-  bus = 0;
-  TwoWire & myWire = Wire;
-#endif
+  TwoWire& myWire = I2cGetWire(bus);
+  if (&myWire == nullptr) { return false; }  // No valid I2c bus
+
   addr &= 0x7F;         // Max I2C address is 127
   if (I2cActive(addr, bus)) {
     return false;       // If already active report as not present;
diff --git a/tasmota/tasmota_xsns_sensor/xsns_66_iAQ.ino b/tasmota/tasmota_xsns_sensor/xsns_66_iAQ.ino
index 55b391a3a..36b966912 100644
--- a/tasmota/tasmota_xsns_sensor/xsns_66_iAQ.ino
+++ b/tasmota/tasmota_xsns_sensor/xsns_66_iAQ.ino
@@ -41,15 +41,48 @@ struct  {
   uint16_t  pred;
   uint16_t  Tvoc;
   uint8_t   i2c_address;
+  uint8_t   i2c_bus;
   uint8_t   status;
   bool      ready;
 } iAQ;
 
+bool IAQ_Read(void) {
+  TwoWire& myWire = I2cGetWire(iAQ.i2c_bus);
+  if (&myWire == nullptr) { return false; }  // No valid I2c bus
+
+  uint8_t buf[9];
+  buf[2] = IAQ_STATUS_I2C_ERR; // populate entry with error code
+  myWire.requestFrom(iAQ.i2c_address, sizeof(buf));
+  for (uint32_t i = 0; i < 9; i++) {
+    buf[i] = myWire.read();
+  }
+  // AddLog(LOG_LEVEL_DEBUG, "iAQ: buffer %x %x %x %x %x %x %x %x %x ", buf[0], buf[1], buf[2], buf[3], buf[4], buf[5], buf[6], buf[7], buf[8]);
+  if (IAQ_STATUS_I2C_ERR == buf[2]) {
+    return false;
+  }
+  iAQ.pred = (buf[0]<<8) + buf[1];
+  iAQ.status = buf[2];
+  iAQ.resistance =  ((uint32_t)buf[3]<<24) + ((uint32_t)buf[4]<<16) + ((uint32_t)buf[5]<<8) + (uint32_t)buf[6];
+  iAQ.Tvoc =  (buf[7]<<8) + buf[8];
+  return true;
+}
+
 void IAQ_Init(void) {
+  for (uint32_t bus = 0; bus < 2; bus++) {
+    if (!I2cSetDevice(I2_ADR_IAQ, bus)) { continue; }
+    iAQ.i2c_address = I2_ADR_IAQ;
+    iAQ.i2c_bus = bus;
+    if (!IAQ_Read()) { continue; }
+    I2cSetActiveFound(I2_ADR_IAQ, "IAQ", bus);
+    iAQ.ready = true;
+  }
+
+/*
   if (!I2cSetDevice(I2_ADR_IAQ)) { return; }
   I2cSetActiveFound(I2_ADR_IAQ, "IAQ");
   iAQ.i2c_address = I2_ADR_IAQ;
   iAQ.ready = true;
+*/
 /*
   for (iAQ.i2c_address = I2_ADR_IAQ; iAQ.i2c_address < I2_ADR_IAQ +5; iAQ.i2c_address++) {
     if (I2cActive(iAQ.i2c_address)) { continue; }
@@ -62,20 +95,6 @@ void IAQ_Init(void) {
 */
 }
 
-void IAQ_Read(void) {
-  uint8_t buf[9];
-  buf[2] = IAQ_STATUS_I2C_ERR; // populate entry with error code
-  Wire.requestFrom(iAQ.i2c_address, sizeof(buf));
-  for( uint32_t i=0; i<9; i++ ) {
-    buf[i]= Wire.read();
-  }
-  // AddLog(LOG_LEVEL_DEBUG, "iAQ: buffer %x %x %x %x %x %x %x %x %x ", buf[0], buf[1], buf[2], buf[3], buf[4], buf[5], buf[6], buf[7], buf[8]);
-  iAQ.pred = (buf[0]<<8) + buf[1];
-  iAQ.status = buf[2];
-  iAQ.resistance =  ((uint32_t)buf[3]<<24) + ((uint32_t)buf[4]<<16) + ((uint32_t)buf[5]<<8) + (uint32_t)buf[6];
-  iAQ.Tvoc =  (buf[7]<<8) + buf[8];
-}
-
 /*********************************************************************************************\
  * Presentation
 \*********************************************************************************************/
diff --git a/tasmota/tasmota_xx2c_global/xx2c_interface.ino b/tasmota/tasmota_xx2c_global/xx2c_interface.ino
index 33e7041d3..55e8a1a0a 100644
--- a/tasmota/tasmota_xx2c_global/xx2c_interface.ino
+++ b/tasmota/tasmota_xx2c_global/xx2c_interface.ino
@@ -413,7 +413,11 @@ const uint8_t kI2cList[] = {
 /*********************************************************************************************/
 
 bool I2cEnabled(uint32_t i2c_index) {
+#ifdef ESP8266
   return (TasmotaGlobal.i2c_enabled && bitRead(Settings->i2c_drivers[i2c_index / 32], i2c_index % 32));
+#else  
+  return ((TasmotaGlobal.i2c_enabled || TasmotaGlobal.i2c_enabled_2) && bitRead(Settings->i2c_drivers[i2c_index / 32], i2c_index % 32));
+#endif
 }
 
 void I2cDriverState(void) {