diff --git a/homeassistant/package_constraints.txt b/homeassistant/package_constraints.txt
index 858d101a3fd..1e4b2a362f5 100644
--- a/homeassistant/package_constraints.txt
+++ b/homeassistant/package_constraints.txt
@@ -29,7 +29,7 @@ cached-ipaddress==0.10.0
 certifi>=2021.5.30
 ciso8601==2.3.2
 cronsim==2.6
-cryptography==45.0.1
+cryptography==45.0.3
 dbus-fast==2.43.0
 fnv-hash-fast==1.5.0
 go2rtc-client==0.1.3b0
diff --git a/pyproject.toml b/pyproject.toml
index a2b87f653a7..b00f7be13b3 100644
--- a/pyproject.toml
+++ b/pyproject.toml
@@ -82,7 +82,7 @@ dependencies = [
   "numpy==2.2.6",
   "PyJWT==2.10.1",
   # PyJWT has loose dependency. We want the latest one.
-  "cryptography==45.0.1",
+  "cryptography==45.0.3",
   "Pillow==11.2.1",
   "propcache==0.3.1",
   "pyOpenSSL==25.1.0",
diff --git a/requirements.txt b/requirements.txt
index 25fea3e0d2d..f66670731e1 100644
--- a/requirements.txt
+++ b/requirements.txt
@@ -34,7 +34,7 @@ lru-dict==1.3.0
 mutagen==1.47.0
 numpy==2.2.6
 PyJWT==2.10.1
-cryptography==45.0.1
+cryptography==45.0.3
 Pillow==11.2.1
 propcache==0.3.1
 pyOpenSSL==25.1.0