diff --git a/homeassistant/components/wmspro/config_flow.py b/homeassistant/components/wmspro/config_flow.py
index c28cf5efce3..2ce58ec9eca 100644
--- a/homeassistant/components/wmspro/config_flow.py
+++ b/homeassistant/components/wmspro/config_flow.py
@@ -84,6 +84,15 @@ class WebControlProConfigFlow(ConfigFlow, domain=DOMAIN):
                 if not pong:
                     errors["base"] = "cannot_connect"
                 else:
+                    await hub.refresh()
+                    rooms = set(hub.rooms.keys())
+                    for entry in self.hass.config_entries.async_loaded_entries(DOMAIN):
+                        if (
+                            entry.runtime_data
+                            and entry.runtime_data.rooms
+                            and set(entry.runtime_data.rooms.keys()) == rooms
+                        ):
+                            return self.async_abort(reason="already_configured")
                     return self.async_create_entry(title=host, data=user_input)
 
         if self.source == dhcp.DOMAIN:
diff --git a/tests/components/wmspro/test_config_flow.py b/tests/components/wmspro/test_config_flow.py
index c25641a8979..782dc051c8c 100644
--- a/tests/components/wmspro/test_config_flow.py
+++ b/tests/components/wmspro/test_config_flow.py
@@ -6,13 +6,19 @@ import aiohttp
 
 from homeassistant.components.dhcp import DhcpServiceInfo
 from homeassistant.components.wmspro.const import DOMAIN
-from homeassistant.config_entries import SOURCE_DHCP, SOURCE_USER
+from homeassistant.config_entries import SOURCE_DHCP, SOURCE_USER, ConfigEntryState
 from homeassistant.const import CONF_HOST
 from homeassistant.core import HomeAssistant
 from homeassistant.data_entry_flow import FlowResultType
 
+from . import setup_config_entry
 
-async def test_config_flow(hass: HomeAssistant, mock_setup_entry: AsyncMock) -> None:
+from tests.common import MockConfigEntry
+
+
+async def test_config_flow(
+    hass: HomeAssistant, mock_setup_entry: AsyncMock, mock_hub_refresh: AsyncMock
+) -> None:
     """Test we can handle user-input to create a config entry."""
     result = await hass.config_entries.flow.async_init(
         DOMAIN, context={"source": SOURCE_USER}
@@ -40,7 +46,7 @@ async def test_config_flow(hass: HomeAssistant, mock_setup_entry: AsyncMock) ->
 
 
 async def test_config_flow_from_dhcp(
-    hass: HomeAssistant, mock_setup_entry: AsyncMock
+    hass: HomeAssistant, mock_setup_entry: AsyncMock, mock_hub_refresh: AsyncMock
 ) -> None:
     """Test we can handle DHCP discovery to create a config entry."""
     info = DhcpServiceInfo(
@@ -74,6 +80,7 @@ async def test_config_flow_from_dhcp(
 async def test_config_flow_from_dhcp_add_mac(
     hass: HomeAssistant,
     mock_setup_entry: AsyncMock,
+    mock_hub_refresh: AsyncMock,
 ) -> None:
     """Test we can use DHCP discovery to add MAC address to a config entry."""
     result = await hass.config_entries.flow.async_init(
@@ -115,6 +122,7 @@ async def test_config_flow_from_dhcp_add_mac(
 async def test_config_flow_from_dhcp_ip_update(
     hass: HomeAssistant,
     mock_setup_entry: AsyncMock,
+    mock_hub_refresh: AsyncMock,
 ) -> None:
     """Test we can use DHCP discovery to update IP in a config entry."""
     info = DhcpServiceInfo(
@@ -160,6 +168,7 @@ async def test_config_flow_from_dhcp_ip_update(
 async def test_config_flow_from_dhcp_no_update(
     hass: HomeAssistant,
     mock_setup_entry: AsyncMock,
+    mock_hub_refresh: AsyncMock,
 ) -> None:
     """Test we do not use DHCP discovery to overwrite hostname with IP in config entry."""
     info = DhcpServiceInfo(
@@ -203,7 +212,7 @@ async def test_config_flow_from_dhcp_no_update(
 
 
 async def test_config_flow_ping_failed(
-    hass: HomeAssistant, mock_setup_entry: AsyncMock
+    hass: HomeAssistant, mock_setup_entry: AsyncMock, mock_hub_refresh: AsyncMock
 ) -> None:
     """Test we handle ping failed error."""
     result = await hass.config_entries.flow.async_init(
@@ -244,7 +253,7 @@ async def test_config_flow_ping_failed(
 
 
 async def test_config_flow_cannot_connect(
-    hass: HomeAssistant, mock_setup_entry: AsyncMock
+    hass: HomeAssistant, mock_setup_entry: AsyncMock, mock_hub_refresh: AsyncMock
 ) -> None:
     """Test we handle cannot connect error."""
     result = await hass.config_entries.flow.async_init(
@@ -285,7 +294,7 @@ async def test_config_flow_cannot_connect(
 
 
 async def test_config_flow_unknown_error(
-    hass: HomeAssistant, mock_setup_entry: AsyncMock
+    hass: HomeAssistant, mock_setup_entry: AsyncMock, mock_hub_refresh: AsyncMock
 ) -> None:
     """Test we handle an unknown error."""
     result = await hass.config_entries.flow.async_init(
@@ -323,3 +332,63 @@ async def test_config_flow_unknown_error(
         CONF_HOST: "1.2.3.4",
     }
     assert len(mock_setup_entry.mock_calls) == 1
+
+
+async def test_config_flow_duplicate_entries(
+    hass: HomeAssistant,
+    mock_config_entry: MockConfigEntry,
+    mock_hub_ping: AsyncMock,
+    mock_dest_refresh: AsyncMock,
+    mock_hub_configuration_test: AsyncMock,
+) -> None:
+    """Test we prevent creation of duplicate config entries."""
+    await setup_config_entry(hass, mock_config_entry)
+    assert mock_config_entry.state is ConfigEntryState.LOADED
+
+    result = await hass.config_entries.flow.async_init(
+        DOMAIN, context={"source": SOURCE_USER}
+    )
+
+    result = await hass.config_entries.flow.async_configure(
+        result["flow_id"],
+        {
+            CONF_HOST: "5.6.7.8",
+        },
+    )
+
+    assert result["type"] is FlowResultType.ABORT
+    assert result["reason"] == "already_configured"
+    assert len(hass.config_entries.async_entries(DOMAIN)) == 1
+
+
+async def test_config_flow_multiple_entries(
+    hass: HomeAssistant,
+    mock_config_entry: MockConfigEntry,
+    mock_hub_ping: AsyncMock,
+    mock_dest_refresh: AsyncMock,
+    mock_hub_configuration_test: AsyncMock,
+    mock_hub_configuration_prod: AsyncMock,
+) -> None:
+    """Test we allow creation of different config entries."""
+    await setup_config_entry(hass, mock_config_entry)
+    assert mock_config_entry.state is ConfigEntryState.LOADED
+
+    mock_hub_configuration_prod.return_value = mock_hub_configuration_test.return_value
+
+    result = await hass.config_entries.flow.async_init(
+        DOMAIN, context={"source": SOURCE_USER}
+    )
+
+    result = await hass.config_entries.flow.async_configure(
+        result["flow_id"],
+        {
+            CONF_HOST: "5.6.7.8",
+        },
+    )
+
+    assert result["type"] is FlowResultType.CREATE_ENTRY
+    assert result["title"] == "5.6.7.8"
+    assert result["data"] == {
+        CONF_HOST: "5.6.7.8",
+    }
+    assert len(hass.config_entries.async_entries(DOMAIN)) == 2