diff --git a/homeassistant/components/opentherm_gw/__init__.py b/homeassistant/components/opentherm_gw/__init__.py
index c6cf14bfdce..71fd104bd2f 100644
--- a/homeassistant/components/opentherm_gw/__init__.py
+++ b/homeassistant/components/opentherm_gw/__init__.py
@@ -43,6 +43,7 @@ from .const import (
     SERVICE_SET_CONTROL_SETPOINT,
     SERVICE_SET_GPIO_MODE,
     SERVICE_SET_HOT_WATER_OVRD,
+    SERVICE_SET_HOT_WATER_SETPOINT,
     SERVICE_SET_LED_MODE,
     SERVICE_SET_MAX_MOD,
     SERVICE_SET_OAT,
@@ -145,6 +146,7 @@ def register_services(hass):
             ),
         }
     )
+    service_set_hot_water_setpoint_schema = service_set_control_setpoint_schema
     service_set_hot_water_ovrd_schema = vol.Schema(
         {
             vol.Required(ATTR_GW_ID): vol.All(
@@ -263,6 +265,21 @@ def register_services(hass):
         service_set_hot_water_ovrd_schema,
     )
 
+    async def set_dhw_setpoint(call):
+        """Set the domestic hot water setpoint on the OpenTherm Gateway."""
+        gw_dev = hass.data[DATA_OPENTHERM_GW][DATA_GATEWAYS][call.data[ATTR_GW_ID]]
+        gw_var = gw_vars.DATA_DHW_SETPOINT
+        value = await gw_dev.gateway.set_dhw_setpoint(call.data[ATTR_TEMPERATURE])
+        gw_dev.status.update({gw_var: value})
+        async_dispatcher_send(hass, gw_dev.update_signal, gw_dev.status)
+
+    hass.services.async_register(
+        DOMAIN,
+        SERVICE_SET_HOT_WATER_SETPOINT,
+        set_dhw_setpoint,
+        service_set_hot_water_setpoint_schema,
+    )
+
     async def set_device_clock(call):
         """Set the clock on the OpenTherm Gateway."""
         gw_dev = hass.data[DATA_OPENTHERM_GW][DATA_GATEWAYS][call.data[ATTR_GW_ID]]
diff --git a/homeassistant/components/opentherm_gw/const.py b/homeassistant/components/opentherm_gw/const.py
index b8d427ba193..14b54366b4a 100644
--- a/homeassistant/components/opentherm_gw/const.py
+++ b/homeassistant/components/opentherm_gw/const.py
@@ -29,6 +29,7 @@ DOMAIN = "opentherm_gw"
 SERVICE_RESET_GATEWAY = "reset_gateway"
 SERVICE_SET_CLOCK = "set_clock"
 SERVICE_SET_CONTROL_SETPOINT = "set_control_setpoint"
+SERVICE_SET_HOT_WATER_SETPOINT = "set_hot_water_setpoint"
 SERVICE_SET_HOT_WATER_OVRD = "set_hot_water_ovrd"
 SERVICE_SET_GPIO_MODE = "set_gpio_mode"
 SERVICE_SET_LED_MODE = "set_led_mode"
diff --git a/homeassistant/components/opentherm_gw/services.yaml b/homeassistant/components/opentherm_gw/services.yaml
index 227c6d423bc..f60648ee8d4 100644
--- a/homeassistant/components/opentherm_gw/services.yaml
+++ b/homeassistant/components/opentherm_gw/services.yaml
@@ -52,6 +52,20 @@ set_hot_water_ovrd:
         state, or "A" to disable the override.
       example: "1"
 
+set_hot_water_setpoint:
+  description: >
+    Set the domestic hot water setpoint on the gateway.
+  fields:
+    gateway_id:
+      description: The gateway_id of the OpenTherm Gateway.
+      example: "opentherm_gateway"
+    temperature:
+      description: >
+        The domestic hot water setpoint to set on the gateway. Not all boilers support this feature.
+        Values between 0 and 90 are accepted, but not all boilers support this range.
+        Check the values of the slave_dhw_min_setp and slave_dhw_max_setp sensors to see the supported range on your boiler.
+      example: "60"
+
 set_gpio_mode:
   description: Change the function of the GPIO pins of the gateway.
   fields: