diff --git a/homeassistant/components/vicare/climate.py b/homeassistant/components/vicare/climate.py
index c8a4781fa0a..9a55da0f219 100644
--- a/homeassistant/components/vicare/climate.py
+++ b/homeassistant/components/vicare/climate.py
@@ -6,6 +6,7 @@ import logging
 from typing import Any
 
 from PyViCare.PyViCareUtils import (
+    PyViCareCommandError,
     PyViCareInvalidDataError,
     PyViCareNotSupportedFeatureError,
     PyViCareRateLimitError,
@@ -354,7 +355,10 @@ class ViCareClimate(ClimateEntity):
         _LOGGER.debug("Setting preset to %s / %s", preset_mode, vicare_program)
         if self._current_program != VICARE_PROGRAM_NORMAL:
             # We can't deactivate "normal"
-            self._circuit.deactivateProgram(self._current_program)
+            try:
+                self._circuit.deactivateProgram(self._current_program)
+            except PyViCareCommandError:
+                _LOGGER.debug("Unable to deactivate program %s", self._current_program)
         if vicare_program != VICARE_PROGRAM_NORMAL:
             # And we can't explicitly activate normal, either
             self._circuit.activateProgram(vicare_program)