diff --git a/homeassistant/components/twitch/manifest.json b/homeassistant/components/twitch/manifest.json
index 810982d0cb4..12ae1d1ee72 100644
--- a/homeassistant/components/twitch/manifest.json
+++ b/homeassistant/components/twitch/manifest.json
@@ -7,5 +7,5 @@
   "documentation": "https://www.home-assistant.io/integrations/twitch",
   "iot_class": "cloud_polling",
   "loggers": ["twitch"],
-  "requirements": ["twitchAPI==4.0.0"]
+  "requirements": ["twitchAPI==4.2.1"]
 }
diff --git a/requirements_all.txt b/requirements_all.txt
index 491748872e2..b34aac62079 100644
--- a/requirements_all.txt
+++ b/requirements_all.txt
@@ -2789,7 +2789,7 @@ twentemilieu==2.0.1
 twilio==6.32.0
 
 # homeassistant.components.twitch
-twitchAPI==4.0.0
+twitchAPI==4.2.1
 
 # homeassistant.components.ukraine_alarm
 uasiren==0.0.1
diff --git a/requirements_test_all.txt b/requirements_test_all.txt
index 938d6e591ca..f0e36e72382 100644
--- a/requirements_test_all.txt
+++ b/requirements_test_all.txt
@@ -2181,7 +2181,7 @@ twentemilieu==2.0.1
 twilio==6.32.0
 
 # homeassistant.components.twitch
-twitchAPI==4.0.0
+twitchAPI==4.2.1
 
 # homeassistant.components.ukraine_alarm
 uasiren==0.0.1