diff --git a/script/setup b/script/setup
index 9df3fdb25d8..782eb510654 100755
--- a/script/setup
+++ b/script/setup
@@ -16,7 +16,7 @@ fi
 
 mkdir -p config
 
-if [ ! -n "$DEVCONTAINER" ];then
+if [ ! -n "$DEVCONTAINER" ] && [ ! -n "$VIRTUAL_ENV" ];then
   python3 -m venv venv
   source venv/bin/activate
 fi
@@ -36,4 +36,4 @@ logger:
   logs:
     homeassistant.components.cloud: debug
 " >> config/configuration.yaml
-fi
\ No newline at end of file
+fi