diff --git a/homeassistant/components/cpuspeed/__init__.py b/homeassistant/components/cpuspeed/__init__.py
index 1c1ebd5084f..a5d6a35459f 100644
--- a/homeassistant/components/cpuspeed/__init__.py
+++ b/homeassistant/components/cpuspeed/__init__.py
@@ -1,12 +1,21 @@
 """The CPU Speed integration."""
+from cpuinfo import cpuinfo
+
 from homeassistant.config_entries import ConfigEntry
 from homeassistant.core import HomeAssistant
 
-from .const import PLATFORMS
+from .const import LOGGER, PLATFORMS
 
 
 async def async_setup_entry(hass: HomeAssistant, entry: ConfigEntry) -> bool:
     """Set up from a config entry."""
+    if not await hass.async_add_executor_job(cpuinfo.get_cpu_info):
+        LOGGER.error(
+            "Unable to get CPU information, the CPU Speed integration "
+            "is not compatible with your system"
+        )
+        return False
+
     hass.config_entries.async_setup_platforms(entry, PLATFORMS)
     return True
 
diff --git a/homeassistant/components/cpuspeed/config_flow.py b/homeassistant/components/cpuspeed/config_flow.py
index 2a6e2bdee8c..4b3c39f148a 100644
--- a/homeassistant/components/cpuspeed/config_flow.py
+++ b/homeassistant/components/cpuspeed/config_flow.py
@@ -3,6 +3,8 @@ from __future__ import annotations
 
 from typing import Any
 
+from cpuinfo import cpuinfo
+
 from homeassistant.config_entries import ConfigFlow
 from homeassistant.const import CONF_NAME
 from homeassistant.data_entry_flow import FlowResult
@@ -27,6 +29,9 @@ class CPUSpeedFlowHandler(ConfigFlow, domain=DOMAIN):
         if user_input is None:
             return self.async_show_form(step_id="user")
 
+        if not await self.hass.async_add_executor_job(cpuinfo.get_cpu_info):
+            return self.async_abort(reason="not_compatible")
+
         return self.async_create_entry(
             title=self._imported_name or "CPU Speed",
             data={},
diff --git a/homeassistant/components/cpuspeed/strings.json b/homeassistant/components/cpuspeed/strings.json
index 948aa9f647c..932ba29e555 100644
--- a/homeassistant/components/cpuspeed/strings.json
+++ b/homeassistant/components/cpuspeed/strings.json
@@ -8,7 +8,8 @@
       }
     },
     "abort": {
-      "alread_configured": "[%key:common::config_flow::abort::single_instance_allowed%]"
+      "alread_configured": "[%key:common::config_flow::abort::single_instance_allowed%]",
+      "not_compatible": "Unable to get CPU information, this integration is not compatible with your system"
     }
   }
 }
diff --git a/homeassistant/components/cpuspeed/translations/en.json b/homeassistant/components/cpuspeed/translations/en.json
index 53536fc663c..4d4205d54e7 100644
--- a/homeassistant/components/cpuspeed/translations/en.json
+++ b/homeassistant/components/cpuspeed/translations/en.json
@@ -1,7 +1,8 @@
 {
     "config": {
         "abort": {
-            "alread_configured": "Already configured. Only a single configuration possible."
+            "alread_configured": "Already configured. Only a single configuration possible.",
+            "not_compatible": "Unable to get CPU information, this integration is not compatible with your system"
         },
         "step": {
             "user": {
diff --git a/tests/components/cpuspeed/conftest.py b/tests/components/cpuspeed/conftest.py
index 1a221e8a08b..97eb668b02e 100644
--- a/tests/components/cpuspeed/conftest.py
+++ b/tests/components/cpuspeed/conftest.py
@@ -2,7 +2,7 @@
 from __future__ import annotations
 
 from collections.abc import Generator
-from unittest.mock import AsyncMock, patch
+from unittest.mock import AsyncMock, MagicMock, patch
 
 import pytest
 
@@ -22,6 +22,20 @@ def mock_config_entry() -> MockConfigEntry:
     )
 
 
+@pytest.fixture
+def mock_cpuinfo_config_flow() -> Generator[MagicMock, None, None]:
+    """Return a mocked get_cpu_info.
+
+    It is only used to check thruthy or falsy values, so it is mocked
+    to return True.
+    """
+    with patch(
+        "homeassistant.components.cpuspeed.config_flow.cpuinfo.get_cpu_info",
+        return_value=True,
+    ) as cpuinfo_mock:
+        yield cpuinfo_mock
+
+
 @pytest.fixture
 def mock_setup_entry() -> Generator[AsyncMock, None, None]:
     """Mock setting up a config entry."""
diff --git a/tests/components/cpuspeed/test_config_flow.py b/tests/components/cpuspeed/test_config_flow.py
index f2ffdebfe16..14563c82bff 100644
--- a/tests/components/cpuspeed/test_config_flow.py
+++ b/tests/components/cpuspeed/test_config_flow.py
@@ -1,6 +1,6 @@
 """Tests for the CPU Speed config flow."""
 
-from unittest.mock import AsyncMock
+from unittest.mock import AsyncMock, MagicMock
 
 from homeassistant.components.cpuspeed.const import DOMAIN
 from homeassistant.config_entries import SOURCE_IMPORT, SOURCE_USER
@@ -17,6 +17,7 @@ from tests.common import MockConfigEntry
 
 async def test_full_user_flow(
     hass: HomeAssistant,
+    mock_cpuinfo_config_flow: MagicMock,
     mock_setup_entry: AsyncMock,
 ) -> None:
     """Test the full user configuration flow."""
@@ -38,10 +39,12 @@ async def test_full_user_flow(
     assert result2.get("data") == {}
 
     assert len(mock_setup_entry.mock_calls) == 1
+    assert len(mock_cpuinfo_config_flow.mock_calls) == 1
 
 
 async def test_already_configured(
     hass: HomeAssistant,
+    mock_cpuinfo_config_flow: MagicMock,
     mock_setup_entry: AsyncMock,
     mock_config_entry: MockConfigEntry,
 ) -> None:
@@ -56,10 +59,12 @@ async def test_already_configured(
     assert result.get("reason") == "already_configured"
 
     assert len(mock_setup_entry.mock_calls) == 0
+    assert len(mock_cpuinfo_config_flow.mock_calls) == 0
 
 
 async def test_import_flow(
     hass: HomeAssistant,
+    mock_cpuinfo_config_flow: MagicMock,
     mock_setup_entry: AsyncMock,
 ) -> None:
     """Test the import configuration flow."""
@@ -74,3 +79,31 @@ async def test_import_flow(
     assert result.get("data") == {}
 
     assert len(mock_setup_entry.mock_calls) == 1
+    assert len(mock_cpuinfo_config_flow.mock_calls) == 1
+
+
+async def test_not_compatible(
+    hass: HomeAssistant,
+    mock_cpuinfo_config_flow: MagicMock,
+    mock_setup_entry: AsyncMock,
+) -> None:
+    """Test we abort the configuration flow when incompatible."""
+    result = await hass.config_entries.flow.async_init(
+        DOMAIN, context={"source": SOURCE_USER}
+    )
+
+    assert result.get("type") == RESULT_TYPE_FORM
+    assert result.get("step_id") == SOURCE_USER
+    assert "flow_id" in result
+
+    mock_cpuinfo_config_flow.return_value = {}
+    result2 = await hass.config_entries.flow.async_configure(
+        result["flow_id"],
+        user_input={},
+    )
+
+    assert result2.get("type") == RESULT_TYPE_ABORT
+    assert result2.get("reason") == "not_compatible"
+
+    assert len(mock_setup_entry.mock_calls) == 0
+    assert len(mock_cpuinfo_config_flow.mock_calls) == 1