diff --git a/homeassistant/helpers/system_info.py b/homeassistant/helpers/system_info.py
index df4c45cd5ed..53866428332 100644
--- a/homeassistant/helpers/system_info.py
+++ b/homeassistant/helpers/system_info.py
@@ -71,7 +71,10 @@ async def async_get_system_info(hass: HomeAssistant) -> dict[str, Any]:
 
     try:
         info_object["user"] = cached_get_user()
-    except KeyError:
+    except (KeyError, OSError):
+        # OSError on python >= 3.13, KeyError on python < 3.13
+        # KeyError can be removed when 3.12 support is dropped
+        # see https://docs.python.org/3/whatsnew/3.13.html
         info_object["user"] = None
 
     if platform.system() == "Darwin":
diff --git a/tests/helpers/test_system_info.py b/tests/helpers/test_system_info.py
index 16b5b8b652b..2c4b95302fc 100644
--- a/tests/helpers/test_system_info.py
+++ b/tests/helpers/test_system_info.py
@@ -93,10 +93,9 @@ async def test_container_installationtype(hass: HomeAssistant) -> None:
         assert info["installation_type"] == "Unsupported Third Party Container"
 
 
-async def test_getuser_keyerror(hass: HomeAssistant) -> None:
-    """Test getuser keyerror."""
-    with patch(
-        "homeassistant.helpers.system_info.cached_get_user", side_effect=KeyError
-    ):
+@pytest.mark.parametrize("error", [KeyError, OSError])
+async def test_getuser_oserror(hass: HomeAssistant, error: Exception) -> None:
+    """Test getuser oserror."""
+    with patch("homeassistant.helpers.system_info.cached_get_user", side_effect=error):
         info = await async_get_system_info(hass)
         assert info["user"] is None