diff --git a/homeassistant/components/iqvia/__init__.py b/homeassistant/components/iqvia/__init__.py
index d730b406896..db0df3a073b 100644
--- a/homeassistant/components/iqvia/__init__.py
+++ b/homeassistant/components/iqvia/__init__.py
@@ -155,6 +155,9 @@ class IQVIAEntity(CoordinatorEntity):
     @callback
     def _handle_coordinator_update(self) -> None:
         """Handle updated data from the coordinator."""
+        if not self.coordinator.last_update_success:
+            return
+
         self.update_from_latest_data()
         self.async_write_ha_state()
 
diff --git a/homeassistant/components/iqvia/sensor.py b/homeassistant/components/iqvia/sensor.py
index e53ee96b1c4..48ec1cf97b1 100644
--- a/homeassistant/components/iqvia/sensor.py
+++ b/homeassistant/components/iqvia/sensor.py
@@ -105,6 +105,7 @@ class ForecastSensor(IQVIAEntity):
     def update_from_latest_data(self):
         """Update the sensor."""
         data = self.coordinator.data.get("Location")
+
         if not data or not data.get("periods"):
             return
 
@@ -142,6 +143,9 @@ class IndexSensor(IQVIAEntity):
     @callback
     def update_from_latest_data(self):
         """Update the sensor."""
+        if not self.coordinator.last_update_success:
+            return
+
         try:
             if self._type in (TYPE_ALLERGY_TODAY, TYPE_ALLERGY_TOMORROW):
                 data = self.coordinator.data.get("Location")