diff --git a/homeassistant/components/usb/__init__.py b/homeassistant/components/usb/__init__.py
index 7fd27b32b9a..115b0fc3de9 100644
--- a/homeassistant/components/usb/__init__.py
+++ b/homeassistant/components/usb/__init__.py
@@ -113,7 +113,7 @@ class USBDiscovery:
 
         try:
             context = Context()
-        except ImportError:
+        except (ImportError, OSError):
             return False
 
         monitor = Monitor.from_netlink(context)
diff --git a/tests/components/usb/test_init.py b/tests/components/usb/test_init.py
index e511fac061e..f7b642c3390 100644
--- a/tests/components/usb/test_init.py
+++ b/tests/components/usb/test_init.py
@@ -243,7 +243,8 @@ async def test_discovered_by_scanner_after_started_no_vid_pid(hass):
     assert len(mock_config_flow.mock_calls) == 0
 
 
-async def test_non_matching_discovered_by_scanner_after_started(hass):
+@pytest.mark.parametrize("exception_type", [ImportError, OSError])
+async def test_non_matching_discovered_by_scanner_after_started(hass, exception_type):
     """Test a device is discovered by the scanner after the started event that does not match."""
     new_usb = [{"domain": "test1", "vid": "4444", "pid": "4444"}]
 
@@ -258,7 +259,7 @@ async def test_non_matching_discovered_by_scanner_after_started(hass):
         )
     ]
 
-    with patch("pyudev.Context", side_effect=ImportError), patch(
+    with patch("pyudev.Context", side_effect=exception_type), patch(
         "homeassistant.components.usb.async_get_usb", return_value=new_usb
     ), patch(
         "homeassistant.components.usb.comports", return_value=mock_comports