diff --git a/homeassistant/components/prusalink/coordinator.py b/homeassistant/components/prusalink/coordinator.py
index 7d4526a8b45..1d1989119fa 100644
--- a/homeassistant/components/prusalink/coordinator.py
+++ b/homeassistant/components/prusalink/coordinator.py
@@ -9,6 +9,7 @@ import logging
 from time import monotonic
 from typing import TypeVar
 
+from httpx import ConnectError
 from pyprusalink import JobInfo, LegacyPrinterStatus, PrinterStatus, PrusaLink
 from pyprusalink.types import InvalidAuth, PrusaLinkError
 
@@ -47,6 +48,8 @@ class PrusaLinkUpdateCoordinator(DataUpdateCoordinator[T], ABC):
             raise UpdateFailed("Invalid authentication") from None
         except PrusaLinkError as err:
             raise UpdateFailed(str(err)) from err
+        except (TimeoutError, ConnectError) as err:
+            raise UpdateFailed("Cannot connect") from err
 
         self.update_interval = self._get_update_interval(data)
         return data
diff --git a/tests/components/prusalink/test_init.py b/tests/components/prusalink/test_init.py
index 2cdc6894eeb..bd0fb84cafd 100644
--- a/tests/components/prusalink/test_init.py
+++ b/tests/components/prusalink/test_init.py
@@ -3,6 +3,7 @@
 from datetime import timedelta
 from unittest.mock import patch
 
+from httpx import ConnectError
 from pyprusalink.types import InvalidAuth, PrusaLinkError
 import pytest
 
@@ -36,7 +37,10 @@ async def test_unloading(
         assert state.state == "unavailable"
 
 
-@pytest.mark.parametrize("exception", [InvalidAuth, PrusaLinkError])
+@pytest.mark.parametrize(
+    "exception",
+    [InvalidAuth, PrusaLinkError, ConnectError("All connection attempts failed")],
+)
 async def test_failed_update(
     hass: HomeAssistant, mock_config_entry: ConfigEntry, exception
 ) -> None: