diff --git a/homeassistant/components/ssdp/__init__.py b/homeassistant/components/ssdp/__init__.py
index ce2901d4f1a..af8f5915f57 100644
--- a/homeassistant/components/ssdp/__init__.py
+++ b/homeassistant/components/ssdp/__init__.py
@@ -56,6 +56,7 @@ ATTR_UPNP_UDN = "UDN"
 ATTR_UPNP_UPC = "UPC"
 ATTR_UPNP_PRESENTATION_URL = "presentationURL"
 
+PRIMARY_MATCH_KEYS = [ATTR_UPNP_MANUFACTURER, "st", ATTR_UPNP_DEVICE_TYPE]
 
 DISCOVERY_MAPPING = {
     "usn": ATTR_SSDP_USN,
@@ -124,7 +125,10 @@ async def async_get_discovery_info_by_udn(
 async def async_setup(hass: HomeAssistant, config: ConfigType) -> bool:
     """Set up the SSDP integration."""
 
-    scanner = hass.data[DOMAIN] = Scanner(hass)
+    integration_matchers = IntegrationMatchers()
+    integration_matchers.async_setup(await async_get_ssdp(hass))
+
+    scanner = hass.data[DOMAIN] = Scanner(hass, integration_matchers)
 
     asyncio.create_task(scanner.async_start())
 
@@ -156,10 +160,57 @@ def _async_headers_match(
     return True
 
 
+class IntegrationMatchers:
+    """Optimized integration matching."""
+
+    def __init__(self) -> None:
+        """Init optimized integration matching."""
+        self._match_by_key: dict[
+            str, dict[str, list[tuple[str, dict[str, str]]]]
+        ] | None = None
+
+    @core_callback
+    def async_setup(
+        self, integration_matchers: dict[str, list[dict[str, str]]]
+    ) -> None:
+        """Build matchers by key.
+
+        Here we convert the primary match keys into their own
+        dicts so we can do lookups of the primary match
+        key to find the match dict.
+        """
+        self._match_by_key = {}
+        for key in PRIMARY_MATCH_KEYS:
+            matchers_by_key = self._match_by_key[key] = {}
+            for domain, matchers in integration_matchers.items():
+                for matcher in matchers:
+                    if match_value := matcher.get(key):
+                        matchers_by_key.setdefault(match_value, []).append(
+                            (domain, matcher)
+                        )
+
+    @core_callback
+    def async_matching_domains(self, info_with_desc: CaseInsensitiveDict) -> set[str]:
+        """Find domains matching the passed CaseInsensitiveDict."""
+        assert self._match_by_key is not None
+        domains = set()
+        for key, matchers_by_key in self._match_by_key.items():
+            if not (match_value := info_with_desc.get(key)):
+                continue
+            for domain, matcher in matchers_by_key.get(match_value, []):
+                if domain in domains:
+                    continue
+                if all(info_with_desc.get(k) == v for (k, v) in matcher.items()):
+                    domains.add(domain)
+        return domains
+
+
 class Scanner:
     """Class to manage SSDP searching and SSDP advertisements."""
 
-    def __init__(self, hass: HomeAssistant) -> None:
+    def __init__(
+        self, hass: HomeAssistant, integration_matchers: IntegrationMatchers
+    ) -> None:
         """Initialize class."""
         self.hass = hass
         self._cancel_scan: Callable[[], None] | None = None
@@ -167,7 +218,7 @@ class Scanner:
         self._callbacks: list[tuple[SsdpCallback, dict[str, str]]] = []
         self._flow_dispatcher: FlowDispatcher | None = None
         self._description_cache: DescriptionCache | None = None
-        self._integration_matchers: dict[str, list[dict[str, str]]] | None = None
+        self.integration_matchers = integration_matchers
 
     @property
     def _ssdp_devices(self) -> list[SsdpDevice]:
@@ -271,7 +322,6 @@ class Scanner:
         requester = AiohttpSessionRequester(session, True, 10)
         self._description_cache = DescriptionCache(requester)
         self._flow_dispatcher = FlowDispatcher(self.hass)
-        self._integration_matchers = await async_get_ssdp(self.hass)
 
         await self._async_start_ssdp_listeners()
 
@@ -323,16 +373,6 @@ class Scanner:
             if _async_headers_match(combined_headers, match_dict)
         ]
 
-    @core_callback
-    def _async_matching_domains(self, info_with_desc: CaseInsensitiveDict) -> set[str]:
-        assert self._integration_matchers is not None
-        domains = set()
-        for domain, matchers in self._integration_matchers.items():
-            for matcher in matchers:
-                if all(info_with_desc.get(k) == v for (k, v) in matcher.items()):
-                    domains.add(domain)
-        return domains
-
     async def _ssdp_listener_callback(
         self, ssdp_device: SsdpDevice, dst: DeviceOrServiceType, source: SsdpSource
     ) -> None:
@@ -351,7 +391,7 @@ class Scanner:
         ssdp_change = SSDP_SOURCE_SSDP_CHANGE_MAPPING[source]
         await _async_process_callbacks(callbacks, discovery_info, ssdp_change)
 
-        for domain in self._async_matching_domains(info_with_desc):
+        for domain in self.integration_matchers.async_matching_domains(info_with_desc):
             _LOGGER.debug("Discovered %s at %s", domain, location)
 
             flow: SSDPFlow = {