diff --git a/homeassistant/components/mold_indicator/__init__.py b/homeassistant/components/mold_indicator/__init__.py
index adadf41b2b0..c426b942af5 100644
--- a/homeassistant/components/mold_indicator/__init__.py
+++ b/homeassistant/components/mold_indicator/__init__.py
@@ -1 +1,26 @@
 """Calculates mold growth indication from temperature and humidity."""
+
+from homeassistant.config_entries import ConfigEntry
+from homeassistant.const import Platform
+from homeassistant.core import HomeAssistant
+
+PLATFORMS = [Platform.SENSOR]
+
+
+async def async_setup_entry(hass: HomeAssistant, entry: ConfigEntry) -> bool:
+    """Set up Mold indicator from a config entry."""
+
+    await hass.config_entries.async_forward_entry_setups(entry, PLATFORMS)
+    entry.async_on_unload(entry.add_update_listener(update_listener))
+
+    return True
+
+
+async def async_unload_entry(hass: HomeAssistant, entry: ConfigEntry) -> bool:
+    """Unload Mold indicator config entry."""
+    return await hass.config_entries.async_unload_platforms(entry, PLATFORMS)
+
+
+async def update_listener(hass: HomeAssistant, entry: ConfigEntry) -> None:
+    """Handle options update."""
+    await hass.config_entries.async_reload(entry.entry_id)
diff --git a/homeassistant/components/mold_indicator/config_flow.py b/homeassistant/components/mold_indicator/config_flow.py
new file mode 100644
index 00000000000..cc8f05c102d
--- /dev/null
+++ b/homeassistant/components/mold_indicator/config_flow.py
@@ -0,0 +1,96 @@
+"""Config flow for Mold indicator."""
+
+from __future__ import annotations
+
+from collections.abc import Mapping
+from typing import Any, cast
+
+import voluptuous as vol
+
+from homeassistant.components.sensor import SensorDeviceClass
+from homeassistant.const import CONF_NAME, Platform
+from homeassistant.helpers.schema_config_entry_flow import (
+    SchemaCommonFlowHandler,
+    SchemaConfigFlowHandler,
+    SchemaFlowFormStep,
+)
+from homeassistant.helpers.selector import (
+    EntitySelector,
+    EntitySelectorConfig,
+    NumberSelector,
+    NumberSelectorConfig,
+    NumberSelectorMode,
+    TextSelector,
+)
+
+from .const import (
+    CONF_CALIBRATION_FACTOR,
+    CONF_INDOOR_HUMIDITY,
+    CONF_INDOOR_TEMP,
+    CONF_OUTDOOR_TEMP,
+    DEFAULT_NAME,
+    DOMAIN,
+)
+
+
+async def validate_duplicate(
+    handler: SchemaCommonFlowHandler, user_input: dict[str, Any]
+) -> dict[str, Any]:
+    """Validate already existing entry."""
+    handler.parent_handler._async_abort_entries_match({**handler.options, **user_input})  # noqa: SLF001
+    return user_input
+
+
+DATA_SCHEMA_OPTIONS = vol.Schema(
+    {
+        vol.Required(CONF_CALIBRATION_FACTOR): NumberSelector(
+            NumberSelectorConfig(min=0, step="any", mode=NumberSelectorMode.BOX)
+        )
+    }
+)
+
+DATA_SCHEMA_CONFIG = vol.Schema(
+    {
+        vol.Required(CONF_NAME, default=DEFAULT_NAME): TextSelector(),
+        vol.Required(CONF_INDOOR_TEMP): EntitySelector(
+            EntitySelectorConfig(
+                domain=Platform.SENSOR, device_class=SensorDeviceClass.TEMPERATURE
+            )
+        ),
+        vol.Required(CONF_INDOOR_HUMIDITY): EntitySelector(
+            EntitySelectorConfig(
+                domain=Platform.SENSOR, device_class=SensorDeviceClass.HUMIDITY
+            )
+        ),
+        vol.Required(CONF_OUTDOOR_TEMP): EntitySelector(
+            EntitySelectorConfig(
+                domain=Platform.SENSOR, device_class=SensorDeviceClass.TEMPERATURE
+            )
+        ),
+    }
+).extend(DATA_SCHEMA_OPTIONS.schema)
+
+
+CONFIG_FLOW = {
+    "user": SchemaFlowFormStep(
+        schema=DATA_SCHEMA_CONFIG,
+        validate_user_input=validate_duplicate,
+    ),
+}
+OPTIONS_FLOW = {
+    "init": SchemaFlowFormStep(
+        DATA_SCHEMA_OPTIONS,
+        validate_user_input=validate_duplicate,
+    )
+}
+
+
+class MoldIndicatorConfigFlowHandler(SchemaConfigFlowHandler, domain=DOMAIN):
+    """Handle a config flow for Mold indicator."""
+
+    config_flow = CONFIG_FLOW
+    options_flow = OPTIONS_FLOW
+
+    def async_config_entry_title(self, options: Mapping[str, Any]) -> str:
+        """Return config entry title."""
+        return cast(str, options[CONF_NAME])
diff --git a/homeassistant/components/mold_indicator/const.py b/homeassistant/components/mold_indicator/const.py
new file mode 100644
index 00000000000..15fdf51bce3
--- /dev/null
+++ b/homeassistant/components/mold_indicator/const.py
@@ -0,0 +1,12 @@
+"""Constants for Mold indicator component."""
+
+from __future__ import annotations
+
+DOMAIN = "mold_indicator"
+
+CONF_CALIBRATION_FACTOR = "calibration_factor"
+CONF_INDOOR_HUMIDITY = "indoor_humidity_sensor"
+CONF_INDOOR_TEMP = "indoor_temp_sensor"
+CONF_OUTDOOR_TEMP = "outdoor_temp_sensor"
+
+DEFAULT_NAME = "Mold Indicator"
diff --git a/homeassistant/components/mold_indicator/manifest.json b/homeassistant/components/mold_indicator/manifest.json
index 5ebccb5f92d..b57f1c471ef 100644
--- a/homeassistant/components/mold_indicator/manifest.json
+++ b/homeassistant/components/mold_indicator/manifest.json
@@ -2,7 +2,9 @@
   "domain": "mold_indicator",
   "name": "Mold Indicator",
   "codeowners": [],
+  "config_flow": true,
   "documentation": "https://www.home-assistant.io/integrations/mold_indicator",
-  "iot_class": "local_polling",
+  "integration_type": "helper",
+  "iot_class": "calculated",
   "quality_scale": "internal"
 }
diff --git a/homeassistant/components/mold_indicator/sensor.py b/homeassistant/components/mold_indicator/sensor.py
index 2d80bc9f6e1..e96f53a17bb 100644
--- a/homeassistant/components/mold_indicator/sensor.py
+++ b/homeassistant/components/mold_indicator/sensor.py
@@ -15,6 +15,7 @@ from homeassistant.components.sensor import (
     SensorEntity,
     SensorStateClass,
 )
+from homeassistant.config_entries import ConfigEntry
 from homeassistant.const import (
     ATTR_UNIT_OF_MEASUREMENT,
     CONF_NAME,
@@ -37,17 +38,19 @@ from homeassistant.helpers.typing import ConfigType, DiscoveryInfoType, StateTyp
 from homeassistant.util.unit_conversion import TemperatureConverter
 from homeassistant.util.unit_system import METRIC_SYSTEM
 
+from .const import (
+    CONF_CALIBRATION_FACTOR,
+    CONF_INDOOR_HUMIDITY,
+    CONF_INDOOR_TEMP,
+    CONF_OUTDOOR_TEMP,
+    DEFAULT_NAME,
+)
+
 _LOGGER = logging.getLogger(__name__)
 
 ATTR_CRITICAL_TEMP = "estimated_critical_temp"
 ATTR_DEWPOINT = "dewpoint"
 
-CONF_CALIBRATION_FACTOR = "calibration_factor"
-CONF_INDOOR_HUMIDITY = "indoor_humidity_sensor"
-CONF_INDOOR_TEMP = "indoor_temp_sensor"
-CONF_OUTDOOR_TEMP = "outdoor_temp_sensor"
-
-DEFAULT_NAME = "Mold Indicator"
 
 MAGNUS_K2 = 17.62
 MAGNUS_K3 = 243.12
@@ -70,7 +73,7 @@ async def async_setup_platform(
     discovery_info: DiscoveryInfoType | None = None,
 ) -> None:
     """Set up MoldIndicator sensor."""
-    name: str = config[CONF_NAME]
+    name: str = config.get(CONF_NAME, DEFAULT_NAME)
     indoor_temp_sensor: str = config[CONF_INDOOR_TEMP]
     outdoor_temp_sensor: str = config[CONF_OUTDOOR_TEMP]
     indoor_humidity_sensor: str = config[CONF_INDOOR_HUMIDITY]
@@ -91,6 +94,33 @@ async def async_setup_platform(
     )
 
 
+async def async_setup_entry(
+    hass: HomeAssistant,
+    entry: ConfigEntry,
+    async_add_entities: AddEntitiesCallback,
+) -> None:
+    """Set up the Mold indicator sensor entry."""
+    name: str = entry.options[CONF_NAME]
+    indoor_temp_sensor: str = entry.options[CONF_INDOOR_TEMP]
+    outdoor_temp_sensor: str = entry.options[CONF_OUTDOOR_TEMP]
+    indoor_humidity_sensor: str = entry.options[CONF_INDOOR_HUMIDITY]
+    calib_factor: float = entry.options[CONF_CALIBRATION_FACTOR]
+
+    async_add_entities(
+        [
+            MoldIndicator(
+                name,
+                hass.config.units is METRIC_SYSTEM,
+                indoor_temp_sensor,
+                outdoor_temp_sensor,
+                indoor_humidity_sensor,
+                calib_factor,
+            )
+        ],
+        False,
+    )
+
+
 class MoldIndicator(SensorEntity):
     """Represents a MoldIndication sensor."""
 
diff --git a/homeassistant/components/mold_indicator/strings.json b/homeassistant/components/mold_indicator/strings.json
new file mode 100644
index 00000000000..2e34bcc1ba1
--- /dev/null
+++ b/homeassistant/components/mold_indicator/strings.json
@@ -0,0 +1,42 @@
+{
+  "config": {
+    "abort": {
+      "already_configured": "[%key:common::config_flow::abort::already_configured_device%]"
+    },
+    "step": {
+      "user": {
+        "description": "Add Mold indicator helper",
+        "data": {
+          "name": "[%key:common::config_flow::data::name%]",
+          "indoor_humidity_sensor": "Indoor humidity sensor",
+          "indoor_temp_sensor": "Indoor temperature sensor",
+          "outdoor_temp_sensor": "Outdoor temperature sensor",
+          "calibration_factor": "Calibration factor"
+        },
+        "data_description": {
+          "name": "Name for the created entity.",
+          "indoor_humidity_sensor": "The entity ID of the indoor humidity sensor.",
+          "indoor_temp_sensor": "The entity ID of the indoor temperature sensor.",
+          "outdoor_temp_sensor": "The entity ID of the outdoor temperature sensor.",
+          "calibration_factor": "Needs to be calibrated to the critical point in the room."
+        }
+      }
+    }
+  },
+  "options": {
+    "abort": {
+      "already_configured": "[%key:common::config_flow::abort::already_configured_device%]"
+    },
+    "step": {
+      "init": {
+        "description": "Adjust the calibration factor as required",
+        "data": {
+          "calibration_factor": "[%key:component::mold_indicator::config::step::user::data::calibration_factor%]"
+        },
+        "data_description": {
+          "calibration_factor": "[%key:component::mold_indicator::config::step::user::data_description::calibration_factor%]"
+        }
+      }
+    }
+  }
+}
diff --git a/homeassistant/generated/config_flows.py b/homeassistant/generated/config_flows.py
index f03c980a2d4..2e38d608bd9 100644
--- a/homeassistant/generated/config_flows.py
+++ b/homeassistant/generated/config_flows.py
@@ -12,6 +12,7 @@ FLOWS = {
         "history_stats",
         "integration",
         "min_max",
+        "mold_indicator",
         "random",
         "statistics",
         "switch_as_x",
diff --git a/homeassistant/generated/integrations.json b/homeassistant/generated/integrations.json
index a01e20909b6..4a6be3f0a1a 100644
--- a/homeassistant/generated/integrations.json
+++ b/homeassistant/generated/integrations.json
@@ -3790,12 +3790,6 @@
       "config_flow": true,
       "iot_class": "local_push"
     },
-    "mold_indicator": {
-      "name": "Mold Indicator",
-      "integration_type": "hub",
-      "config_flow": false,
-      "iot_class": "local_polling"
-    },
     "monessen": {
       "name": "Monessen",
       "integration_type": "virtual",
@@ -7307,6 +7301,12 @@
       "config_flow": true,
       "iot_class": "calculated"
     },
+    "mold_indicator": {
+      "name": "Mold Indicator",
+      "integration_type": "helper",
+      "config_flow": true,
+      "iot_class": "calculated"
+    },
     "random": {
       "name": "Random",
       "integration_type": "helper",
diff --git a/tests/components/mold_indicator/conftest.py b/tests/components/mold_indicator/conftest.py
new file mode 100644
index 00000000000..11f07e1db35
--- /dev/null
+++ b/tests/components/mold_indicator/conftest.py
@@ -0,0 +1,90 @@
+"""Fixtures for the Mold indicator integration."""
+
+from __future__ import annotations
+
+from collections.abc import Generator
+from typing import Any
+from unittest.mock import AsyncMock, patch
+
+import pytest
+
+from homeassistant.components.mold_indicator.const import (
+    CONF_CALIBRATION_FACTOR,
+    CONF_INDOOR_HUMIDITY,
+    CONF_INDOOR_TEMP,
+    CONF_OUTDOOR_TEMP,
+    DEFAULT_NAME,
+    DOMAIN,
+)
+from homeassistant.config_entries import SOURCE_USER
+from homeassistant.const import (
+    ATTR_UNIT_OF_MEASUREMENT,
+    CONF_NAME,
+    PERCENTAGE,
+    UnitOfTemperature,
+)
+from homeassistant.core import HomeAssistant
+
+from tests.common import MockConfigEntry
+
+
+@pytest.fixture
+def mock_setup_entry() -> Generator[AsyncMock]:
+    """Automatically path mold indicator."""
+    with patch(
+        "homeassistant.components.mold_indicator.async_setup_entry",
+        return_value=True,
+    ) as mock_setup_entry:
+        yield mock_setup_entry
+
+
+@pytest.fixture(name="get_config")
+async def get_config_to_integration_load() -> dict[str, Any]:
+    """Return configuration.
+
+    To override the config, tests can be marked with:
+    @pytest.mark.parametrize("get_config", [{...}])
+    """
+    return {
+        CONF_NAME: DEFAULT_NAME,
+        CONF_INDOOR_TEMP: "sensor.indoor_temp",
+        CONF_INDOOR_HUMIDITY: "sensor.indoor_humidity",
+        CONF_OUTDOOR_TEMP: "sensor.outdoor_temp",
+        CONF_CALIBRATION_FACTOR: 2.0,
+    }
+
+
+@pytest.fixture(name="loaded_entry")
+async def load_integration(
+    hass: HomeAssistant, get_config: dict[str, Any]
+) -> MockConfigEntry:
+    """Set up the Mold indicator integration in Home Assistant."""
+    config_entry = MockConfigEntry(
+        domain=DOMAIN,
+        source=SOURCE_USER,
+        options=get_config,
+        entry_id="1",
+        title=DEFAULT_NAME,
+    )
+
+    config_entry.add_to_hass(hass)
+
+    await hass.config_entries.async_setup(config_entry.entry_id)
+    await hass.async_block_till_done()
+
+    hass.states.async_set(
+        "sensor.indoor_temp",
+        "10",
+        {ATTR_UNIT_OF_MEASUREMENT: UnitOfTemperature.CELSIUS},
+    )
+    hass.states.async_set(
+        "sensor.outdoor_temp",
+        "10",
+        {ATTR_UNIT_OF_MEASUREMENT: UnitOfTemperature.CELSIUS},
+    )
+    hass.states.async_set(
+        "sensor.indoor_humidity", "0", {ATTR_UNIT_OF_MEASUREMENT: PERCENTAGE}
+    )
+    await hass.async_block_till_done()
+
+    return config_entry
diff --git a/tests/components/mold_indicator/test_config_flow.py b/tests/components/mold_indicator/test_config_flow.py
new file mode 100644
index 00000000000..7a766be11f5
--- /dev/null
+++ b/tests/components/mold_indicator/test_config_flow.py
@@ -0,0 +1,115 @@
+"""Test the Mold indicator config flow."""
+
+from __future__ import annotations
+
+from unittest.mock import AsyncMock
+
+from homeassistant.components.mold_indicator.const import (
+    CONF_CALIBRATION_FACTOR,
+    CONF_INDOOR_HUMIDITY,
+    CONF_INDOOR_TEMP,
+    CONF_OUTDOOR_TEMP,
+    DEFAULT_NAME,
+    DOMAIN,
+)
+from homeassistant.config_entries import SOURCE_USER
+from homeassistant.const import CONF_NAME
+from homeassistant.core import HomeAssistant
+from homeassistant.data_entry_flow import FlowResultType
+
+from tests.common import MockConfigEntry
+
+
+async def test_form_sensor(hass: HomeAssistant, mock_setup_entry: AsyncMock) -> None:
+    """Test we get the form for sensor."""
+
+    result = await hass.config_entries.flow.async_init(
+        DOMAIN, context={"source": SOURCE_USER}
+    )
+    assert result["step_id"] == "user"
+    assert result["type"] is FlowResultType.FORM
+
+    result = await hass.config_entries.flow.async_configure(
+        result["flow_id"],
+        {
+            CONF_NAME: DEFAULT_NAME,
+            CONF_INDOOR_TEMP: "sensor.indoor_temp",
+            CONF_INDOOR_HUMIDITY: "sensor.indoor_humidity",
+            CONF_OUTDOOR_TEMP: "sensor.outdoor_temp",
+            CONF_CALIBRATION_FACTOR: 2.0,
+        },
+    )
+
+    assert result["type"] is FlowResultType.CREATE_ENTRY
+    assert result["title"] == DEFAULT_NAME
+    assert result["version"] == 1
+    assert result["options"] == {
+        CONF_NAME: DEFAULT_NAME,
+        CONF_INDOOR_TEMP: "sensor.indoor_temp",
+        CONF_INDOOR_HUMIDITY: "sensor.indoor_humidity",
+        CONF_OUTDOOR_TEMP: "sensor.outdoor_temp",
+        CONF_CALIBRATION_FACTOR: 2.0,
+    }
+
+    assert len(mock_setup_entry.mock_calls) == 1
+
+
+async def test_options_flow(hass: HomeAssistant, loaded_entry: MockConfigEntry) -> None:
+    """Test options flow."""
+
+    result = await hass.config_entries.options.async_init(loaded_entry.entry_id)
+
+    assert result["type"] is FlowResultType.FORM
+    assert result["step_id"] == "init"
+
+    result = await hass.config_entries.options.async_configure(
+        result["flow_id"],
+        user_input={
+            CONF_CALIBRATION_FACTOR: 3.0,
+        },
+    )
+    await hass.async_block_till_done()
+
+    assert result["type"] is FlowResultType.CREATE_ENTRY
+    assert result["data"] == {
+        CONF_NAME: DEFAULT_NAME,
+        CONF_INDOOR_TEMP: "sensor.indoor_temp",
+        CONF_INDOOR_HUMIDITY: "sensor.indoor_humidity",
+        CONF_OUTDOOR_TEMP: "sensor.outdoor_temp",
+        CONF_CALIBRATION_FACTOR: 3.0,
+    }
+
+    await hass.async_block_till_done()
+
+    # Check the entity was updated, no new entity was created
+    # 3 input entities + resulting mold indicator sensor
+    assert len(hass.states.async_all()) == 4
+
+    state = hass.states.get("sensor.mold_indicator")
+    assert state is not None
+
+
+async def test_entry_already_exist(
+    hass: HomeAssistant, loaded_entry: MockConfigEntry
+) -> None:
+    """Test abort when entry already exist."""
+
+    result = await hass.config_entries.flow.async_init(
+        DOMAIN, context={"source": SOURCE_USER}
+    )
+    assert result["step_id"] == "user"
+    assert result["type"] is FlowResultType.FORM
+
+    result = await hass.config_entries.flow.async_configure(
+        result["flow_id"],
+        {
+            CONF_NAME: DEFAULT_NAME,
+            CONF_INDOOR_TEMP: "sensor.indoor_temp",
+            CONF_INDOOR_HUMIDITY: "sensor.indoor_humidity",
+            CONF_OUTDOOR_TEMP: "sensor.outdoor_temp",
+            CONF_CALIBRATION_FACTOR: 2.0,
+        },
+    )
+
+    assert result["type"] is FlowResultType.ABORT
+    assert result["reason"] == "already_configured"
diff --git a/tests/components/mold_indicator/test_init.py b/tests/components/mold_indicator/test_init.py
new file mode 100644
index 00000000000..5fd6b11c8fe
--- /dev/null
+++ b/tests/components/mold_indicator/test_init.py
@@ -0,0 +1,17 @@
+"""Test Mold indicator component setup process."""
+
+from __future__ import annotations
+
+from homeassistant.config_entries import ConfigEntryState
+from homeassistant.core import HomeAssistant
+
+from tests.common import MockConfigEntry
+
+
+async def test_unload_entry(hass: HomeAssistant, loaded_entry: MockConfigEntry) -> None:
+    """Test unload an entry."""
+
+    assert loaded_entry.state is ConfigEntryState.LOADED
+    assert await hass.config_entries.async_unload(loaded_entry.entry_id)
+    await hass.async_block_till_done()
+    assert loaded_entry.state is ConfigEntryState.NOT_LOADED
diff --git a/tests/components/mold_indicator/test_sensor.py b/tests/components/mold_indicator/test_sensor.py
index 2de1d34b403..bb3f7c4fc93 100644
--- a/tests/components/mold_indicator/test_sensor.py
+++ b/tests/components/mold_indicator/test_sensor.py
@@ -16,6 +16,8 @@ from homeassistant.const import (
 from homeassistant.core import HomeAssistant
 from homeassistant.setup import async_setup_component
 
+from tests.common import MockConfigEntry
+
 
 @pytest.fixture(autouse=True)
 def init_sensors_fixture(hass: HomeAssistant) -> None:
@@ -52,6 +54,16 @@ async def test_setup(hass: HomeAssistant) -> None:
     assert moldind.attributes.get("unit_of_measurement") == PERCENTAGE
 
 
+async def test_setup_from_config_entry(
+    hass: HomeAssistant, loaded_entry: MockConfigEntry
+) -> None:
+    """Test the mold indicator sensor setup from a config entry."""
+
+    moldind = hass.states.get("sensor.mold_indicator")
+    assert moldind
+    assert moldind.attributes.get("unit_of_measurement") == PERCENTAGE
+
+
 async def test_invalidcalib(hass: HomeAssistant) -> None:
     """Test invalid sensor values."""
     hass.states.async_set(