diff --git a/homeassistant/helpers/intent.py b/homeassistant/helpers/intent.py
index 649819a5f06..c93545ed414 100644
--- a/homeassistant/helpers/intent.py
+++ b/homeassistant/helpers/intent.py
@@ -215,6 +215,9 @@ class MatchFailedReason(Enum):
     DUPLICATE_NAME = auto()
     """Two or more entities matched the same name constraint and could not be disambiguated."""
 
+    MULTIPLE_TARGETS = auto()
+    """Two or more entities matched when a single target is required."""
+
     def is_no_entities_reason(self) -> bool:
         """Return True if the match failed because no entities matched."""
         return self not in (
@@ -255,6 +258,9 @@ class MatchTargetsConstraints:
     allow_duplicate_names: bool = False
     """True if entities with duplicate names are allowed in result."""
 
+    single_target: bool = False
+    """True if result must contain a single target."""
+
     @property
     def has_constraints(self) -> bool:
         """Returns True if at least one constraint is set (ignores assistant)."""
@@ -266,6 +272,7 @@ class MatchTargetsConstraints:
             or self.device_classes
             or self.features
             or self.states
+            or self.single_target
         )
 
 
@@ -291,7 +298,7 @@ class MatchTargetsResult:
     """Reason for failed match when is_match = False."""
 
     states: list[State] = field(default_factory=list)
-    """List of matched entity states when is_match = True."""
+    """List of matched entity states."""
 
     no_match_name: str | None = None
     """Name of invalid area/floor or duplicate name when match fails for those reasons."""
@@ -357,7 +364,6 @@ class MatchTargetsCandidate:
     is_exposed: bool
     entity: entity_registry.RegistryEntry | None = None
     area: area_registry.AreaEntry | None = None
-    floor: floor_registry.FloorEntry | None = None
     device: device_registry.DeviceEntry | None = None
     matched_name: str | None = None
 
@@ -549,6 +555,7 @@ def async_match_targets(  # noqa: C901
         or constraints.device_classes
         or constraints.area_name
         or constraints.floor_name
+        or constraints.single_target
     ):
         if constraints.assistant:
             # Check exposure
@@ -719,6 +726,48 @@ def async_match_targets(  # noqa: C901
 
         candidates = final_candidates
 
+    if constraints.single_target and len(candidates) > 1:
+        # Find best match using preferences
+        if not (preferences.area_id or preferences.floor_id):
+            # No preferences
+            return MatchTargetsResult(
+                False,
+                MatchFailedReason.MULTIPLE_TARGETS,
+                states=[c.state for c in candidates],
+            )
+
+        if not areas_added:
+            ar = area_registry.async_get(hass)
+            dr = device_registry.async_get(hass)
+            _add_areas(ar, dr, candidates)
+            areas_added = True
+
+        filtered_candidates: list[MatchTargetsCandidate] = candidates
+        if preferences.area_id:
+            # Filter by area
+            filtered_candidates = [
+                c for c in candidates if c.area and (c.area.id == preferences.area_id)
+            ]
+
+        if (len(filtered_candidates) > 1) and preferences.floor_id:
+            # Filter by floor
+            filtered_candidates = [
+                c
+                for c in candidates
+                if c.area and (c.area.floor_id == preferences.floor_id)
+            ]
+
+        if len(filtered_candidates) != 1:
+            # Filtering could not restrict to a single target
+            return MatchTargetsResult(
+                False,
+                MatchFailedReason.MULTIPLE_TARGETS,
+                states=[c.state for c in candidates],
+            )
+
+        # Filtering succeeded
+        candidates = filtered_candidates
+
     return MatchTargetsResult(
         True,
         None,
diff --git a/tests/helpers/test_intent.py b/tests/helpers/test_intent.py
index ae8c2ed65d0..bf0df305c35 100644
--- a/tests/helpers/test_intent.py
+++ b/tests/helpers/test_intent.py
@@ -234,7 +234,7 @@ async def test_async_match_targets(
 
     # Floor 2
     floor_2 = floor_registry.async_create("second floor", aliases={"upstairs"})
-    area_bedroom_2 = area_registry.async_get_or_create("bedroom")
+    area_bedroom_2 = area_registry.async_get_or_create("second floor bedroom")
     area_bedroom_2 = area_registry.async_update(
         area_bedroom_2.id, floor_id=floor_2.floor_id
     )
@@ -269,7 +269,7 @@ async def test_async_match_targets(
 
     # Floor 3
     floor_3 = floor_registry.async_create("third floor", aliases={"upstairs"})
-    area_bedroom_3 = area_registry.async_get_or_create("bedroom")
+    area_bedroom_3 = area_registry.async_get_or_create("third floor bedroom")
     area_bedroom_3 = area_registry.async_update(
         area_bedroom_3.id, floor_id=floor_3.floor_id
     )
@@ -510,6 +510,37 @@ async def test_async_match_targets(
         bathroom_light_3.entity_id,
     }
 
+    # Check single target constraint
+    result = intent.async_match_targets(
+        hass,
+        intent.MatchTargetsConstraints(domains={"light"}, single_target=True),
+        states=states,
+    )
+    assert not result.is_match
+    assert result.no_match_reason == intent.MatchFailedReason.MULTIPLE_TARGETS
+
+    # Only one light on the ground floor
+    result = intent.async_match_targets(
+        hass,
+        intent.MatchTargetsConstraints(domains={"light"}, single_target=True),
+        preferences=intent.MatchTargetsPreferences(floor_id=floor_1.floor_id),
+        states=states,
+    )
+    assert result.is_match
+    assert len(result.states) == 1
+    assert result.states[0].entity_id == bathroom_light_1.entity_id
+
+    # Only one switch in bedroom
+    result = intent.async_match_targets(
+        hass,
+        intent.MatchTargetsConstraints(domains={"switch"}, single_target=True),
+        preferences=intent.MatchTargetsPreferences(area_id=area_bedroom_2.id),
+        states=states,
+    )
+    assert result.is_match
+    assert len(result.states) == 1
+    assert result.states[0].entity_id == bedroom_switch_2.entity_id
+
 
 async def test_match_device_area(
     hass: HomeAssistant,