diff --git a/.github/workflows/builder.yml b/.github/workflows/builder.yml
index d21a1ba73a1..01827fce4a6 100644
--- a/.github/workflows/builder.yml
+++ b/.github/workflows/builder.yml
@@ -126,7 +126,7 @@ jobs:
         env:
           UV_PRERELEASE: allow
         run: |
-          python3 -m pip install "$(grep '^uv' < requirements_test.txt)"
+          python3 -m pip install "$(grep '^uv' < requirements.txt)"
           uv pip install packaging tomli
           uv pip install .
           python3 script/version_bump.py nightly --set-nightly-version "${{ needs.init.outputs.version }}"
diff --git a/.github/workflows/ci.yaml b/.github/workflows/ci.yaml
index 84ee815c087..45e7ec77a8e 100644
--- a/.github/workflows/ci.yaml
+++ b/.github/workflows/ci.yaml
@@ -252,7 +252,7 @@ jobs:
           python -m venv venv
           . venv/bin/activate
           python --version
-          pip install "$(grep '^uv' < requirements_test.txt)"
+          pip install "$(grep '^uv' < requirements.txt)"
           uv pip install "$(cat requirements_test.txt | grep pre-commit)"
       - name: Restore pre-commit environment from cache
         id: cache-precommit
@@ -476,7 +476,7 @@ jobs:
       - name: Generate partial uv restore key
         id: generate-uv-key
         run: |
-          uv_version=$(cat requirements_test.txt | grep uv | cut -d '=' -f 3)
+          uv_version=$(cat requirements.txt | grep uv | cut -d '=' -f 3)
           echo "version=${uv_version}" >> $GITHUB_OUTPUT
           echo "key=uv-${{ env.UV_CACHE_VERSION }}-${uv_version}-${{
             env.HA_SHORT_VERSION }}-$(date -u '+%Y-%m-%dT%H:%M:%s')" >> $GITHUB_OUTPUT
@@ -525,7 +525,7 @@ jobs:
           python -m venv venv
           . venv/bin/activate
           python --version
-          pip install "$(grep '^uv' < requirements_test.txt)"
+          pip install "$(grep '^uv' < requirements.txt)"
           uv pip install -U "pip>=21.3.1" setuptools wheel
           uv pip install -r requirements.txt
           python -m script.gen_requirements_all ci
diff --git a/.github/workflows/wheels.yml b/.github/workflows/wheels.yml
index 20dd2054c6e..2ba72411330 100644
--- a/.github/workflows/wheels.yml
+++ b/.github/workflows/wheels.yml
@@ -46,7 +46,7 @@ jobs:
           python -m venv venv
           . venv/bin/activate
           python --version
-          pip install "$(grep '^uv' < requirements_test.txt)"
+          pip install "$(grep '^uv' < requirements.txt)"
           uv pip install -r requirements.txt
 
       - name: Get information
diff --git a/.pre-commit-config.yaml b/.pre-commit-config.yaml
index d87ccf93aa7..98a4eecb641 100644
--- a/.pre-commit-config.yaml
+++ b/.pre-commit-config.yaml
@@ -83,7 +83,7 @@ repos:
         pass_filenames: false
         language: script
         types: [text]
-        files: ^(homeassistant/.+/(icons|manifest|strings)\.json|homeassistant/brands/.*\.json|homeassistant/.+/services\.yaml|script/hassfest/(?!metadata|mypy_config).+\.py|requirements_test.txt)$
+        files: ^(homeassistant/.+/(icons|manifest|strings)\.json|homeassistant/brands/.*\.json|homeassistant/.+/services\.yaml|script/hassfest/(?!metadata|mypy_config).+\.py|requirements.+\.txt)$
       - id: hassfest-metadata
         name: hassfest-metadata
         entry: script/run-in-env.sh python3 -m script.hassfest -p metadata
diff --git a/homeassistant/package_constraints.txt b/homeassistant/package_constraints.txt
index 8731a0158b7..a416eab6506 100644
--- a/homeassistant/package_constraints.txt
+++ b/homeassistant/package_constraints.txt
@@ -42,7 +42,6 @@ orjson==3.10.7
 packaging>=23.1
 paho-mqtt==1.6.1
 Pillow==10.4.0
-pip>=21.3.1
 psutil-home-assistant==0.0.1
 PyJWT==2.9.0
 pymicro-vad==1.0.1
@@ -59,6 +58,7 @@ SQLAlchemy==2.0.31
 typing-extensions>=4.12.2,<5.0
 ulid-transform==1.0.2
 urllib3>=1.26.5,<2
+uv==0.4.8
 voluptuous-openapi==0.0.5
 voluptuous-serialize==2.6.0
 voluptuous==0.15.2
diff --git a/homeassistant/util/package.py b/homeassistant/util/package.py
index 067bf5ff36d..4d87e51badc 100644
--- a/homeassistant/util/package.py
+++ b/homeassistant/util/package.py
@@ -94,12 +94,11 @@ def install_package(
 
     Return boolean if install successful.
     """
-    # Not using 'import pip; pip.main([])' because it breaks the logger
     _LOGGER.info("Attempting install of %s", package)
     env = os.environ.copy()
-    args = [sys.executable, "-m", "pip", "install", "--quiet", package]
+    args = ["uv", "pip", "install", "--quiet", package]
     if timeout:
-        args += ["--timeout", str(timeout)]
+        env["HTTP_TIMEOUT"] = str(timeout)
     if upgrade:
         args.append("--upgrade")
     if constraints is not None:
@@ -109,7 +108,7 @@ def install_package(
         # This only works if not running in venv
         args += ["--user"]
         env["PYTHONUSERBASE"] = os.path.abspath(target)
-    _LOGGER.debug("Running pip command: args=%s", args)
+    _LOGGER.debug("Running uv pip command: args=%s", args)
     with Popen(
         args,
         stdin=PIPE,
diff --git a/pyproject.toml b/pyproject.toml
index ac362b92483..e0f427454b4 100644
--- a/pyproject.toml
+++ b/pyproject.toml
@@ -54,7 +54,6 @@ dependencies    = [
     "pyOpenSSL==24.2.1",
     "orjson==3.10.7",
     "packaging>=23.1",
-    "pip>=21.3.1",
     "psutil-home-assistant==0.0.1",
     "python-slugify==8.0.4",
     "PyYAML==6.0.2",
@@ -66,6 +65,7 @@ dependencies    = [
     # Temporary setting an upper bound, to prevent compat issues with urllib3>=2
     # https://github.com/home-assistant/core/issues/97248
     "urllib3>=1.26.5,<2",
+    "uv==0.4.8",
     "voluptuous==0.15.2",
     "voluptuous-serialize==2.6.0",
     "voluptuous-openapi==0.0.5",
diff --git a/requirements.txt b/requirements.txt
index 2a46b3170d1..eb39a94559a 100644
--- a/requirements.txt
+++ b/requirements.txt
@@ -29,7 +29,6 @@ Pillow==10.4.0
 pyOpenSSL==24.2.1
 orjson==3.10.7
 packaging>=23.1
-pip>=21.3.1
 psutil-home-assistant==0.0.1
 python-slugify==8.0.4
 PyYAML==6.0.2
@@ -38,6 +37,7 @@ SQLAlchemy==2.0.31
 typing-extensions>=4.12.2,<5.0
 ulid-transform==1.0.2
 urllib3>=1.26.5,<2
+uv==0.4.8
 voluptuous==0.15.2
 voluptuous-serialize==2.6.0
 voluptuous-openapi==0.0.5
diff --git a/requirements_test.txt b/requirements_test.txt
index 6869cc12e11..7579a654d40 100644
--- a/requirements_test.txt
+++ b/requirements_test.txt
@@ -51,4 +51,3 @@ types-pytz==2024.1.0.20240417
 types-PyYAML==6.0.12.20240311
 types-requests==2.31.0.3
 types-xmltodict==0.13.0.3
-uv==0.4.8
diff --git a/script/hassfest/docker.py b/script/hassfest/docker.py
index 5809ea4afa0..bcafbdb53c0 100644
--- a/script/hassfest/docker.py
+++ b/script/hassfest/docker.py
@@ -172,8 +172,9 @@ def _generate_files(config: Config) -> list[File]:
         + 10
     ) * 1000
 
-    package_versions = _get_package_versions(
-        Path("requirements_test.txt"), {"pipdeptree", "tqdm", "uv"}
+    package_versions = _get_package_versions(Path("requirements.txt"), {"uv"})
+    package_versions |= _get_package_versions(
+        Path("requirements_test.txt"), {"pipdeptree", "tqdm"}
     )
     package_versions |= _get_package_versions(
         Path("requirements_test_pre_commit.txt"), {"ruff"}
diff --git a/tests/util/test_package.py b/tests/util/test_package.py
index 2ead327bf10..72600f94890 100644
--- a/tests/util/test_package.py
+++ b/tests/util/test_package.py
@@ -1,12 +1,13 @@
 """Test Home Assistant package util methods."""
 
 import asyncio
+from collections.abc import Generator
 from importlib.metadata import metadata
 import logging
 import os
 from subprocess import PIPE
 import sys
-from unittest.mock import MagicMock, call, patch
+from unittest.mock import MagicMock, Mock, call, patch
 
 import pytest
 
@@ -24,7 +25,7 @@ TEST_ZIP_REQ = "file://{}#{}".format(
 
 
 @pytest.fixture
-def mock_sys():
+def mock_sys() -> Generator[MagicMock]:
     """Mock sys."""
     with patch("homeassistant.util.package.sys", spec=object) as sys_mock:
         sys_mock.executable = "python3"
@@ -32,19 +33,19 @@ def mock_sys():
 
 
 @pytest.fixture
-def deps_dir():
+def deps_dir() -> str:
     """Return path to deps directory."""
     return os.path.abspath("/deps_dir")
 
 
 @pytest.fixture
-def lib_dir(deps_dir):
+def lib_dir(deps_dir) -> str:
     """Return path to lib directory."""
     return os.path.join(deps_dir, "lib_dir")
 
 
 @pytest.fixture
-def mock_popen(lib_dir):
+def mock_popen(lib_dir) -> Generator[MagicMock]:
     """Return a Popen mock."""
     with patch("homeassistant.util.package.Popen") as popen_mock:
         popen_mock.return_value.__enter__ = popen_mock
@@ -57,7 +58,7 @@ def mock_popen(lib_dir):
 
 
 @pytest.fixture
-def mock_env_copy():
+def mock_env_copy() -> Generator[Mock]:
     """Mock os.environ.copy."""
     with patch("homeassistant.util.package.os.environ.copy") as env_copy:
         env_copy.return_value = {}
@@ -65,14 +66,14 @@ def mock_env_copy():
 
 
 @pytest.fixture
-def mock_venv():
+def mock_venv() -> Generator[MagicMock]:
     """Mock homeassistant.util.package.is_virtual_env."""
     with patch("homeassistant.util.package.is_virtual_env") as mock:
         mock.return_value = True
         yield mock
 
 
-def mock_async_subprocess():
+def mock_async_subprocess() -> Generator[MagicMock]:
     """Return an async Popen mock."""
     async_popen = MagicMock()
 
@@ -85,13 +86,14 @@ def mock_async_subprocess():
     return async_popen
 
 
-def test_install(mock_sys, mock_popen, mock_env_copy, mock_venv) -> None:
+@pytest.mark.usefixtures("mock_sys", "mock_venv")
+def test_install(mock_popen: MagicMock, mock_env_copy: MagicMock) -> None:
     """Test an install attempt on a package that doesn't exist."""
     env = mock_env_copy()
     assert package.install_package(TEST_NEW_REQ, False)
     assert mock_popen.call_count == 2
     assert mock_popen.mock_calls[0] == call(
-        [mock_sys.executable, "-m", "pip", "install", "--quiet", TEST_NEW_REQ],
+        ["uv", "pip", "install", "--quiet", TEST_NEW_REQ],
         stdin=PIPE,
         stdout=PIPE,
         stderr=PIPE,
@@ -101,15 +103,33 @@ def test_install(mock_sys, mock_popen, mock_env_copy, mock_venv) -> None:
     assert mock_popen.return_value.communicate.call_count == 1
 
 
-def test_install_upgrade(mock_sys, mock_popen, mock_env_copy, mock_venv) -> None:
+@pytest.mark.usefixtures("mock_sys", "mock_venv")
+def test_install_with_timeout(mock_popen: MagicMock, mock_env_copy: MagicMock) -> None:
+    """Test an install attempt on a package that doesn't exist with a timeout set."""
+    env = mock_env_copy()
+    assert package.install_package(TEST_NEW_REQ, False, timeout=10)
+    assert mock_popen.call_count == 2
+    env["HTTP_TIMEOUT"] = "10"
+    assert mock_popen.mock_calls[0] == call(
+        ["uv", "pip", "install", "--quiet", TEST_NEW_REQ],
+        stdin=PIPE,
+        stdout=PIPE,
+        stderr=PIPE,
+        env=env,
+        close_fds=False,
+    )
+    assert mock_popen.return_value.communicate.call_count == 1
+
+
+@pytest.mark.usefixtures("mock_sys", "mock_venv")
+def test_install_upgrade(mock_popen, mock_env_copy) -> None:
     """Test an upgrade attempt on a package."""
     env = mock_env_copy()
     assert package.install_package(TEST_NEW_REQ)
     assert mock_popen.call_count == 2
     assert mock_popen.mock_calls[0] == call(
         [
-            mock_sys.executable,
-            "-m",
+            "uv",
             "pip",
             "install",
             "--quiet",
@@ -133,8 +153,7 @@ def test_install_target(mock_sys, mock_popen, mock_env_copy, mock_venv) -> None:
     mock_venv.return_value = False
     mock_sys.platform = "linux"
     args = [
-        mock_sys.executable,
-        "-m",
+        "uv",
         "pip",
         "install",
         "--quiet",
@@ -150,16 +169,16 @@ def test_install_target(mock_sys, mock_popen, mock_env_copy, mock_venv) -> None:
     assert mock_popen.return_value.communicate.call_count == 1
 
 
-def test_install_target_venv(mock_sys, mock_popen, mock_env_copy, mock_venv) -> None:
+@pytest.mark.usefixtures("mock_sys", "mock_popen", "mock_env_copy", "mock_venv")
+def test_install_target_venv() -> None:
     """Test an install with a target in a virtual environment."""
     target = "target_folder"
     with pytest.raises(AssertionError):
         package.install_package(TEST_NEW_REQ, False, target=target)
 
 
-def test_install_error(
-    caplog: pytest.LogCaptureFixture, mock_sys, mock_popen, mock_venv
-) -> None:
+@pytest.mark.usefixtures("mock_sys", "mock_venv")
+def test_install_error(caplog: pytest.LogCaptureFixture, mock_popen) -> None:
     """Test an install that errors out."""
     caplog.set_level(logging.WARNING)
     mock_popen.return_value.returncode = 1
@@ -169,7 +188,8 @@ def test_install_error(
         assert record.levelname == "ERROR"
 
 
-def test_install_constraint(mock_sys, mock_popen, mock_env_copy, mock_venv) -> None:
+@pytest.mark.usefixtures("mock_sys", "mock_venv")
+def test_install_constraint(mock_popen, mock_env_copy) -> None:
     """Test install with constraint file on not installed package."""
     env = mock_env_copy()
     constraints = "constraints_file.txt"
@@ -177,8 +197,7 @@ def test_install_constraint(mock_sys, mock_popen, mock_env_copy, mock_venv) -> N
     assert mock_popen.call_count == 2
     assert mock_popen.mock_calls[0] == call(
         [
-            mock_sys.executable,
-            "-m",
+            "uv",
             "pip",
             "install",
             "--quiet",