diff --git a/homeassistant/components/thermoworks_smoke/manifest.json b/homeassistant/components/thermoworks_smoke/manifest.json
index 43ce96dd012..7baec9cdb74 100644
--- a/homeassistant/components/thermoworks_smoke/manifest.json
+++ b/homeassistant/components/thermoworks_smoke/manifest.json
@@ -2,6 +2,7 @@
   "domain": "thermoworks_smoke",
   "name": "ThermoWorks Smoke",
   "codeowners": [],
+  "disabled": "This integration is disabled because it creates an unresolvable dependency conflict.",
   "documentation": "https://www.home-assistant.io/integrations/thermoworks_smoke",
   "iot_class": "cloud_polling",
   "loggers": ["thermoworks_smoke"],
diff --git a/requirements_all.txt b/requirements_all.txt
index eb1c8a21932..f6452b08e72 100644
--- a/requirements_all.txt
+++ b/requirements_all.txt
@@ -2719,7 +2719,6 @@ streamlabswater==1.0.1
 
 # homeassistant.components.huawei_lte
 # homeassistant.components.solaredge
-# homeassistant.components.thermoworks_smoke
 # homeassistant.components.traccar
 stringcase==1.2.0
 
@@ -2797,9 +2796,6 @@ thermobeacon-ble==0.7.0
 # homeassistant.components.thermopro
 thermopro-ble==0.10.0
 
-# homeassistant.components.thermoworks_smoke
-thermoworks-smoke==0.1.8
-
 # homeassistant.components.thingspeak
 thingspeak==1.0.0
 
diff --git a/requirements_test_all.txt b/requirements_test_all.txt
index fb2d4931173..c74fe22299d 100644
--- a/requirements_test_all.txt
+++ b/requirements_test_all.txt
@@ -2159,7 +2159,6 @@ streamlabswater==1.0.1
 
 # homeassistant.components.huawei_lte
 # homeassistant.components.solaredge
-# homeassistant.components.thermoworks_smoke
 # homeassistant.components.traccar
 stringcase==1.2.0