diff --git a/CODEOWNERS b/CODEOWNERS
index 4a5b6b0d56e..ec098523744 100644
--- a/CODEOWNERS
+++ b/CODEOWNERS
@@ -305,7 +305,7 @@ homeassistant/components/ohmconnect/* @robbiet480
 homeassistant/components/ombi/* @larssont
 homeassistant/components/omnilogic/* @oliver84 @djtimca @gentoosu
 homeassistant/components/onboarding/* @home-assistant/core
-homeassistant/components/onewire/* @garbled1
+homeassistant/components/onewire/* @garbled1 @epenet
 homeassistant/components/onvif/* @hunterjm
 homeassistant/components/openerz/* @misialq
 homeassistant/components/opengarage/* @danielhiversen
diff --git a/homeassistant/components/onewire/const.py b/homeassistant/components/onewire/const.py
index af68135af10..23a686767b0 100644
--- a/homeassistant/components/onewire/const.py
+++ b/homeassistant/components/onewire/const.py
@@ -1,12 +1,18 @@
 """Constants for 1-Wire component."""
+from homeassistant.components.sensor import DOMAIN as SENSOR_DOMAIN
+
 CONF_MOUNT_DIR = "mount_dir"
 CONF_NAMES = "names"
 
+CONF_TYPE_OWFS = "OWFS"
+CONF_TYPE_OWSERVER = "OWServer"
+CONF_TYPE_SYSBUS = "SysBus"
+
 DEFAULT_OWSERVER_PORT = 4304
 DEFAULT_SYSBUS_MOUNT_DIR = "/sys/bus/w1/devices/"
 
 DOMAIN = "onewire"
 
 SUPPORTED_PLATFORMS = [
-    "sensor",
+    SENSOR_DOMAIN,
 ]
diff --git a/homeassistant/components/onewire/manifest.json b/homeassistant/components/onewire/manifest.json
index f812454ae59..42ef7e54603 100644
--- a/homeassistant/components/onewire/manifest.json
+++ b/homeassistant/components/onewire/manifest.json
@@ -2,6 +2,6 @@
   "domain": "onewire",
   "name": "1-Wire",
   "documentation": "https://www.home-assistant.io/integrations/onewire",
-  "requirements": ["pyownet==0.10.0.post1"],
-  "codeowners": ["@garbled1"]
+  "requirements": ["pyownet==0.10.0.post1", "pi1wire==0.1.0"],
+  "codeowners": ["@garbled1", "@epenet"]
 }
diff --git a/homeassistant/components/onewire/sensor.py b/homeassistant/components/onewire/sensor.py
index 2ac00c814b2..4c6564b2fec 100644
--- a/homeassistant/components/onewire/sensor.py
+++ b/homeassistant/components/onewire/sensor.py
@@ -2,8 +2,13 @@
 from glob import glob
 import logging
 import os
-import time
 
+from pi1wire import (
+    InvalidCRCException,
+    NotFoundSensorException,
+    Pi1Wire,
+    UnsupportResponseException,
+)
 from pyownet import protocol
 import voluptuous as vol
 
@@ -23,6 +28,9 @@ from homeassistant.helpers.entity import Entity
 from .const import (
     CONF_MOUNT_DIR,
     CONF_NAMES,
+    CONF_TYPE_OWFS,
+    CONF_TYPE_OWSERVER,
+    CONF_TYPE_SYSBUS,
     DEFAULT_OWSERVER_PORT,
     DEFAULT_SYSBUS_MOUNT_DIR,
 )
@@ -54,6 +62,8 @@ DEVICE_SENSORS = {
     "EF": {"HobbyBoard": "special"},
 }
 
+DEVICE_SUPPORT_SYSBUS = ["10", "22", "28", "3B", "42"]
+
 # EF sensors are usually hobbyboards specialized sensors.
 # These can only be read by OWFS.  Currently this driver only supports them
 # via owserver (network protocol)
@@ -120,18 +130,32 @@ def hb_info_from_type(dev_type="std"):
 
 def setup_platform(hass, config, add_entities, discovery_info=None):
     """Set up 1-Wire platform."""
-    base_dir = config[CONF_MOUNT_DIR]
-    owport = config[CONF_PORT]
-    owhost = config.get(CONF_HOST)
+    entities = get_entities(config)
+    add_entities(entities, True)
 
-    devs = []
+
+def get_entities(config):
+    """Get a list of entities."""
+    base_dir = config[CONF_MOUNT_DIR]
+    owhost = config.get(CONF_HOST)
+    owport = config[CONF_PORT]
+
+    # Ensure type is configured
+    if owhost:
+        conf_type = CONF_TYPE_OWSERVER
+    elif base_dir == DEFAULT_SYSBUS_MOUNT_DIR:
+        conf_type = CONF_TYPE_SYSBUS
+    else:
+        conf_type = CONF_TYPE_OWFS
+
+    entities = []
     device_names = {}
     if CONF_NAMES in config:
         if isinstance(config[CONF_NAMES], dict):
             device_names = config[CONF_NAMES]
 
     # We have an owserver on a remote(or local) host/port
-    if owhost:
+    if conf_type == CONF_TYPE_OWSERVER:
         _LOGGER.debug("Initializing using %s:%s", owhost, owport)
         try:
             owproxy = protocol.proxy(host=owhost, port=owport)
@@ -166,7 +190,7 @@ def setup_platform(hass, config, add_entities, discovery_info=None):
                         sensor_key = f"wetness_{s_id}"
                 sensor_id = os.path.split(os.path.split(device)[0])[1]
                 device_file = os.path.join(os.path.split(device)[0], sensor_value)
-                devs.append(
+                entities.append(
                     OneWireProxy(
                         device_names.get(sensor_id, sensor_id),
                         device_file,
@@ -176,19 +200,34 @@ def setup_platform(hass, config, add_entities, discovery_info=None):
                 )
 
     # We have a raw GPIO ow sensor on a Pi
-    elif base_dir == DEFAULT_SYSBUS_MOUNT_DIR:
-        _LOGGER.debug("Initializing using SysBus %s", base_dir)
-        for device_family in DEVICE_SENSORS:
-            for device_folder in glob(os.path.join(base_dir, f"{device_family}[.-]*")):
-                sensor_id = os.path.split(device_folder)[1]
-                device_file = os.path.join(device_folder, "w1_slave")
-                devs.append(
-                    OneWireDirect(
-                        device_names.get(sensor_id, sensor_id),
-                        device_file,
-                        "temperature",
-                    )
+    elif conf_type == CONF_TYPE_SYSBUS:
+        _LOGGER.debug("Initializing using SysBus")
+        for p1sensor in Pi1Wire().find_all_sensors():
+            family = p1sensor.mac_address[:2]
+            sensor_id = f"{family}-{p1sensor.mac_address[2:]}"
+            if family not in DEVICE_SUPPORT_SYSBUS:
+                _LOGGER.warning(
+                    "Ignoring unknown family (%s) of sensor found for device: %s",
+                    family,
+                    sensor_id,
                 )
+                continue
+
+            device_file = f"/sys/bus/w1/devices/{sensor_id}/w1_slave"
+            entities.append(
+                OneWireDirect(
+                    device_names.get(sensor_id, sensor_id),
+                    device_file,
+                    "temperature",
+                    p1sensor,
+                )
+            )
+        if not entities:
+            _LOGGER.error(
+                "No onewire sensor found. Check if dtoverlay=w1-gpio "
+                "is in your /boot/config.txt. "
+                "Check the mount_dir parameter if it's defined"
+            )
 
     # We have an owfs mounted
     else:
@@ -204,7 +243,7 @@ def setup_platform(hass, config, add_entities, discovery_info=None):
                     device_file = os.path.join(
                         os.path.split(family_file_path)[0], sensor_value
                     )
-                    devs.append(
+                    entities.append(
                         OneWireOWFS(
                             device_names.get(sensor_id, sensor_id),
                             device_file,
@@ -212,15 +251,7 @@ def setup_platform(hass, config, add_entities, discovery_info=None):
                         )
                     )
 
-    if devs == []:
-        _LOGGER.error(
-            "No onewire sensor found. Check if dtoverlay=w1-gpio "
-            "is in your /boot/config.txt. "
-            "Check the mount_dir parameter if it's defined"
-        )
-        return
-
-    add_entities(devs, True)
+    return entities
 
 
 class OneWire(Entity):
@@ -234,12 +265,6 @@ class OneWire(Entity):
         self._state = None
         self._value_raw = None
 
-    def _read_value_raw(self):
-        """Read the value as it is returned by the sensor."""
-        with open(self._device_file) as ds_device_file:
-            lines = ds_device_file.readlines()
-        return lines
-
     @property
     def name(self):
         """Return the name of the sensor."""
@@ -300,24 +325,36 @@ class OneWireProxy(OneWire):
 class OneWireDirect(OneWire):
     """Implementation of a 1-Wire sensor directly connected to RPI GPIO."""
 
+    def __init__(self, name, device_file, sensor_type, owsensor):
+        """Initialize the sensor."""
+        super().__init__(name, device_file, sensor_type)
+        self._owsensor = owsensor
+
     def update(self):
         """Get the latest data from the device."""
         value = None
-        lines = self._read_value_raw()
-        while lines[0].strip()[-3:] != "YES":
-            time.sleep(0.2)
-            lines = self._read_value_raw()
-        equals_pos = lines[1].find("t=")
-        if equals_pos != -1:
-            value_string = lines[1][equals_pos + 2 :]
-            value = round(float(value_string) / 1000.0, 1)
-            self._value_raw = float(value_string)
+        try:
+            self._value_raw = self._owsensor.get_temperature()
+            value = round(float(self._value_raw), 1)
+        except (
+            FileNotFoundError,
+            InvalidCRCException,
+            NotFoundSensorException,
+            UnsupportResponseException,
+        ) as ex:
+            _LOGGER.warning("Cannot read from sensor %s: %s", self._device_file, ex)
         self._state = value
 
 
 class OneWireOWFS(OneWire):
     """Implementation of a 1-Wire sensor through owfs."""
 
+    def _read_value_raw(self):
+        """Read the value as it is returned by the sensor."""
+        with open(self._device_file) as ds_device_file:
+            lines = ds_device_file.readlines()
+        return lines
+
     def update(self):
         """Get the latest data from the device."""
         value = None
diff --git a/requirements_all.txt b/requirements_all.txt
index 0aa29d30307..e17aa1cb7ac 100644
--- a/requirements_all.txt
+++ b/requirements_all.txt
@@ -1087,6 +1087,9 @@ pencompy==0.0.3
 # homeassistant.components.unifi_direct
 pexpect==4.6.0
 
+# homeassistant.components.onewire
+pi1wire==0.1.0
+
 # homeassistant.components.pi4ioe5v9xxxx
 pi4ioe5v9xxxx==0.0.2
 
diff --git a/requirements_test_all.txt b/requirements_test_all.txt
index d9e4227da7a..4e1e3855dcc 100644
--- a/requirements_test_all.txt
+++ b/requirements_test_all.txt
@@ -516,6 +516,9 @@ pdunehd==1.3.2
 # homeassistant.components.unifi_direct
 pexpect==4.6.0
 
+# homeassistant.components.onewire
+pi1wire==0.1.0
+
 # homeassistant.components.pilight
 pilight==0.1.1
 
@@ -773,6 +776,9 @@ pyotp==2.3.0
 # homeassistant.components.openweathermap
 pyowm==2.10.0
 
+# homeassistant.components.onewire
+pyownet==0.10.0.post1
+
 # homeassistant.components.point
 pypoint==1.1.2
 
diff --git a/tests/components/onewire/test_entity_sysbus.py b/tests/components/onewire/test_entity_sysbus.py
new file mode 100644
index 00000000000..4667ab641e7
--- /dev/null
+++ b/tests/components/onewire/test_entity_sysbus.py
@@ -0,0 +1,129 @@
+"""Tests for 1-Wire temperature sensor (device family 10, 22, 28, 3B, 42) connected on SysBus."""
+from datetime import datetime, timedelta
+from unittest.mock import PropertyMock, patch
+
+from pi1wire import (
+    InvalidCRCException,
+    NotFoundSensorException,
+    UnsupportResponseException,
+)
+
+from homeassistant.components.onewire.const import (
+    DEFAULT_OWSERVER_PORT,
+    DEFAULT_SYSBUS_MOUNT_DIR,
+    DOMAIN,
+)
+from homeassistant.components.sensor import DOMAIN as SENSOR_DOMAIN
+from homeassistant.const import TEMP_CELSIUS
+from homeassistant.setup import async_setup_component
+
+from tests.common import async_fire_time_changed, mock_registry
+
+MOCK_DEVICE_ID = "28-111111111111"
+MOCK_DEVICE_NAME = "My DS18B20"
+MOCK_ENTITY_ID = "sensor.my_ds18b20_temperature"
+
+
+async def test_onewiredirect_setup_valid_device(hass):
+    """Test that sysbus config entry works correctly."""
+    entity_registry = mock_registry(hass)
+    config = {
+        "sensor": {
+            "platform": DOMAIN,
+            "mount_dir": DEFAULT_SYSBUS_MOUNT_DIR,
+            "port": DEFAULT_OWSERVER_PORT,
+            "names": {
+                MOCK_DEVICE_ID: MOCK_DEVICE_NAME,
+            },
+        }
+    }
+
+    with patch(
+        "homeassistant.components.onewire.sensor.Pi1Wire"
+    ) as mock_pi1wire, patch("pi1wire.OneWire") as mock_owsensor:
+        type(mock_owsensor).mac_address = PropertyMock(
+            return_value=MOCK_DEVICE_ID.replace("-", "")
+        )
+        mock_owsensor.get_temperature.side_effect = [
+            25.123,
+            FileNotFoundError,
+            25.223,
+            InvalidCRCException,
+            25.323,
+            NotFoundSensorException,
+            25.423,
+            UnsupportResponseException,
+            25.523,
+        ]
+        mock_pi1wire.return_value.find_all_sensors.return_value = [mock_owsensor]
+        assert await async_setup_component(hass, SENSOR_DOMAIN, config)
+        await hass.async_block_till_done()
+
+        assert len(entity_registry.entities) == 1
+        registry_entry = entity_registry.entities.get(MOCK_ENTITY_ID)
+        assert registry_entry is not None
+        assert (
+            registry_entry.unique_id == f"/sys/bus/w1/devices/{MOCK_DEVICE_ID}/w1_slave"
+        )
+        assert registry_entry.unit_of_measurement == TEMP_CELSIUS
+
+        # 25.123
+        current_time = datetime.now()
+        state = hass.states.get(MOCK_ENTITY_ID)
+        assert state.state == "25.1"
+
+        # FileNotFoundError
+        current_time = current_time + timedelta(minutes=2)
+        async_fire_time_changed(hass, current_time)
+        await hass.async_block_till_done()
+        state = hass.states.get(MOCK_ENTITY_ID)
+        assert state.state == "unknown"
+
+        # 25.223
+        current_time = current_time + timedelta(minutes=2)
+        async_fire_time_changed(hass, current_time)
+        await hass.async_block_till_done()
+        state = hass.states.get(MOCK_ENTITY_ID)
+        assert state.state == "25.2"
+
+        # InvalidCRCException
+        current_time = current_time + timedelta(minutes=2)
+        async_fire_time_changed(hass, current_time)
+        await hass.async_block_till_done()
+        state = hass.states.get(MOCK_ENTITY_ID)
+        assert state.state == "unknown"
+
+        # 25.323
+        current_time = current_time + timedelta(minutes=2)
+        async_fire_time_changed(hass, current_time)
+        await hass.async_block_till_done()
+        state = hass.states.get(MOCK_ENTITY_ID)
+        assert state.state == "25.3"
+
+        # NotFoundSensorException
+        current_time = current_time + timedelta(minutes=2)
+        async_fire_time_changed(hass, current_time)
+        await hass.async_block_till_done()
+        state = hass.states.get(MOCK_ENTITY_ID)
+        assert state.state == "unknown"
+
+        # 25.423
+        current_time = current_time + timedelta(minutes=2)
+        async_fire_time_changed(hass, current_time)
+        await hass.async_block_till_done()
+        state = hass.states.get(MOCK_ENTITY_ID)
+        assert state.state == "25.4"
+
+        # UnsupportResponseException
+        current_time = current_time + timedelta(minutes=2)
+        async_fire_time_changed(hass, current_time)
+        await hass.async_block_till_done()
+        state = hass.states.get(MOCK_ENTITY_ID)
+        assert state.state == "unknown"
+
+        # 25.523
+        current_time = current_time + timedelta(minutes=2)
+        async_fire_time_changed(hass, current_time)
+        await hass.async_block_till_done()
+        state = hass.states.get(MOCK_ENTITY_ID)
+        assert state.state == "25.5"