diff --git a/homeassistant/components/recorder/migration.py b/homeassistant/components/recorder/migration.py
index eadfc543b59..bc636d34b10 100644
--- a/homeassistant/components/recorder/migration.py
+++ b/homeassistant/components/recorder/migration.py
@@ -712,6 +712,17 @@ def _apply_update(  # noqa: C901
     elif new_version == 29:
         # Recreate statistics_meta index to block duplicated statistic_id
         _drop_index(session_maker, "statistics_meta", "ix_statistics_meta_statistic_id")
+        if engine.dialect.name == SupportedDialect.MYSQL:
+            # Ensure the row format is dynamic or the index
+            # unique will be too large
+            with session_scope(session=session_maker()) as session:
+                connection = session.connection()
+                # This is safe to run multiple times and fast since the table is small
+                connection.execute(
+                    text(
+                        "ALTER TABLE statistics_meta ENGINE=InnoDB, ROW_FORMAT=DYNAMIC"
+                    )
+                )
         try:
             _create_index(
                 session_maker, "statistics_meta", "ix_statistics_meta_statistic_id"