diff --git a/homeassistant/package_constraints.txt b/homeassistant/package_constraints.txt
index afeab239043..395e107f7fb 100644
--- a/homeassistant/package_constraints.txt
+++ b/homeassistant/package_constraints.txt
@@ -138,7 +138,7 @@ pyOpenSSL>=24.0.0
 
 # protobuf must be in package constraints for the wheel
 # builder to build binary wheels
-protobuf==4.25.4
+protobuf==5.28.2
 
 # faust-cchardet: Ensure we have a version we can build wheels
 # 2.1.18 is the first version that works with our wheel builder
diff --git a/pyproject.toml b/pyproject.toml
index ae0f3b7fc76..ca7718ac47a 100644
--- a/pyproject.toml
+++ b/pyproject.toml
@@ -532,8 +532,6 @@ filterwarnings = [
     # -- other
     # Locale changes might take some time to resolve upstream
     "ignore:'locale.getdefaultlocale' is deprecated and slated for removal in Python 3.15:DeprecationWarning:micloud.micloud",
-    # https://github.com/protocolbuffers/protobuf - v4.25.4
-    "ignore:Type google._upb._message.(Message|Scalar)MapContainer uses PyType_Spec with a metaclass that has custom tp_new. .* Python 3.14:DeprecationWarning",
     # https://github.com/MatsNl/pyatag/issues/11 - v0.3.7.1
     "ignore:datetime.*utcnow\\(\\) is deprecated and scheduled for removal:DeprecationWarning:pyatag.gateway",
     # https://github.com/lidatong/dataclasses-json/issues/328
diff --git a/script/gen_requirements_all.py b/script/gen_requirements_all.py
index 88da57f343e..0496350fc27 100755
--- a/script/gen_requirements_all.py
+++ b/script/gen_requirements_all.py
@@ -157,7 +157,7 @@ pyOpenSSL>=24.0.0
 
 # protobuf must be in package constraints for the wheel
 # builder to build binary wheels
-protobuf==4.25.4
+protobuf==5.28.2
 
 # faust-cchardet: Ensure we have a version we can build wheels
 # 2.1.18 is the first version that works with our wheel builder