diff --git a/Dockerfile b/Dockerfile
index 2f6a400e0d1..b6d571f308e 100644
--- a/Dockerfile
+++ b/Dockerfile
@@ -7,7 +7,8 @@ FROM ${BUILD_FROM}
 # Synchronize with homeassistant/core.py:async_stop
 ENV \
     S6_SERVICES_GRACETIME=240000 \
-    UV_SYSTEM_PYTHON=true
+    UV_SYSTEM_PYTHON=true \
+    UV_NO_CACHE=true
 
 ARG QEMU_CPU
 
diff --git a/script/hassfest/docker.py b/script/hassfest/docker.py
index 1f6c19e6593..083cdaba1a9 100644
--- a/script/hassfest/docker.py
+++ b/script/hassfest/docker.py
@@ -20,7 +20,8 @@ FROM ${{BUILD_FROM}}
 # Synchronize with homeassistant/core.py:async_stop
 ENV \
     S6_SERVICES_GRACETIME={timeout} \
-    UV_SYSTEM_PYTHON=true
+    UV_SYSTEM_PYTHON=true \
+    UV_NO_CACHE=true
 
 ARG QEMU_CPU