diff --git a/homeassistant/components/iqvia/__init__.py b/homeassistant/components/iqvia/__init__.py
index 38d29aeffb2..b0f7086cad7 100644
--- a/homeassistant/components/iqvia/__init__.py
+++ b/homeassistant/components/iqvia/__init__.py
@@ -51,6 +51,10 @@ async def async_setup_entry(hass: HomeAssistant, entry: ConfigEntry) -> bool:
     websession = aiohttp_client.async_get_clientsession(hass)
     client = Client(entry.data[CONF_ZIP_CODE], session=websession)
 
+    # We disable the client's request retry abilities here to avoid a lengthy (and
+    # blocking) startup:
+    client.disable_request_retries()
+
     async def async_get_data_from_api(
         api_coro: Callable[..., Awaitable]
     ) -> dict[str, Any]:
@@ -90,6 +94,9 @@ async def async_setup_entry(hass: HomeAssistant, entry: ConfigEntry) -> bool:
         # API calls fail:
         raise ConfigEntryNotReady()
 
+    # Once we've successfully authenticated, we re-enable client request retries:
+    client.enable_request_retries()
+
     hass.data.setdefault(DOMAIN, {})
     hass.data[DOMAIN][entry.entry_id] = coordinators
 
diff --git a/homeassistant/components/iqvia/manifest.json b/homeassistant/components/iqvia/manifest.json
index 3ac1ffd31f9..f78ca1e258c 100644
--- a/homeassistant/components/iqvia/manifest.json
+++ b/homeassistant/components/iqvia/manifest.json
@@ -3,7 +3,7 @@
   "name": "IQVIA",
   "config_flow": true,
   "documentation": "https://www.home-assistant.io/integrations/iqvia",
-  "requirements": ["numpy==1.21.4", "pyiqvia==1.1.0"],
+  "requirements": ["numpy==1.21.4", "pyiqvia==2021.11.0"],
   "codeowners": ["@bachya"],
   "iot_class": "cloud_polling"
 }
diff --git a/requirements_all.txt b/requirements_all.txt
index 7b08015b8f7..8327ac75675 100644
--- a/requirements_all.txt
+++ b/requirements_all.txt
@@ -1556,7 +1556,7 @@ pyipma==2.0.5
 pyipp==0.11.0
 
 # homeassistant.components.iqvia
-pyiqvia==1.1.0
+pyiqvia==2021.11.0
 
 # homeassistant.components.irish_rail_transport
 pyirishrail==0.0.2
diff --git a/requirements_test_all.txt b/requirements_test_all.txt
index b1e4b52a2fa..bccd9f18359 100644
--- a/requirements_test_all.txt
+++ b/requirements_test_all.txt
@@ -944,7 +944,7 @@ pyipma==2.0.5
 pyipp==0.11.0
 
 # homeassistant.components.iqvia
-pyiqvia==1.1.0
+pyiqvia==2021.11.0
 
 # homeassistant.components.isy994
 pyisy==3.0.0