diff --git a/homeassistant/components/orangepi_gpio/const.py b/homeassistant/components/orangepi_gpio/const.py
index 47ddf5b7085..f663fbc1ef4 100644
--- a/homeassistant/components/orangepi_gpio/const.py
+++ b/homeassistant/components/orangepi_gpio/const.py
@@ -10,6 +10,8 @@ from orangepi import (
     pc2,
     pcplus,
     pi3,
+    pi4,
+    pi4B,
     plus2e,
     prime,
     r1,
@@ -27,14 +29,18 @@ CONF_PIN_MODE = "pin_mode"
 CONF_PORTS = "ports"
 DEFAULT_INVERT_LOGIC = False
 PIN_MODES = {
+    "duo": duo.BOARD,
     "lite": lite.BOARD,
     "lite2": lite2.BOARD,
+    "neocore2": neocore2.BOARD,
     "one": one.BOARD,
     "oneplus": oneplus.BOARD,
     "pc": pc.BOARD,
     "pc2": pc2.BOARD,
     "pcplus": pcplus.BOARD,
     "pi3": pi3.BOARD,
+    "pi4": pi4.BOARD,
+    "pi4B": pi4B.BOARD,
     "plus2e": plus2e.BOARD,
     "prime": prime.BOARD,
     "r1": r1.BOARD,
@@ -42,8 +48,6 @@ PIN_MODES = {
     "zero": zero.BOARD,
     "zeroplus": zeroplus.BOARD,
     "zeroplus2": zeroplus2.BOARD,
-    "duo": duo.BOARD,
-    "neocore2": neocore2.BOARD,
 }
 
 _SENSORS_SCHEMA = vol.Schema({cv.positive_int: cv.string})
diff --git a/homeassistant/components/orangepi_gpio/manifest.json b/homeassistant/components/orangepi_gpio/manifest.json
index 7d96756a8d1..9b5f567c420 100644
--- a/homeassistant/components/orangepi_gpio/manifest.json
+++ b/homeassistant/components/orangepi_gpio/manifest.json
@@ -2,7 +2,7 @@
   "domain": "orangepi_gpio",
   "name": "Orange Pi GPIO",
   "documentation": "https://www.home-assistant.io/integrations/orangepi_gpio",
-  "requirements": ["OPi.GPIO==0.4.0"],
+  "requirements": ["OPi.GPIO==0.5.2"],
   "codeowners": ["@pascallj"],
   "iot_class": "local_push"
 }
diff --git a/requirements_all.txt b/requirements_all.txt
index 8f9ff72c97c..1c9178b070c 100644
--- a/requirements_all.txt
+++ b/requirements_all.txt
@@ -20,7 +20,7 @@ HAP-python==4.3.0
 Mastodon.py==1.5.1
 
 # homeassistant.components.orangepi_gpio
-OPi.GPIO==0.4.0
+OPi.GPIO==0.5.2
 
 # homeassistant.components.flick_electric
 PyFlick==0.0.2