diff --git a/homeassistant/package_constraints.txt b/homeassistant/package_constraints.txt
index ab6da7293f0..c80b4a0416c 100644
--- a/homeassistant/package_constraints.txt
+++ b/homeassistant/package_constraints.txt
@@ -17,7 +17,7 @@ cryptography==35.0.0
 emoji==1.5.0
 hass-nabucasa==0.50.0
 home-assistant-frontend==20211117.0
-httpx==0.19.0
+httpx==0.21.0
 ifaddr==0.1.7
 jinja2==3.0.3
 paho-mqtt==1.6.1
diff --git a/requirements.txt b/requirements.txt
index 0049df1cf7a..a7e86ca6dea 100644
--- a/requirements.txt
+++ b/requirements.txt
@@ -11,7 +11,7 @@ backports.zoneinfo;python_version<"3.9"
 bcrypt==3.1.7
 certifi>=2021.5.30
 ciso8601==2.2.0
-httpx==0.19.0
+httpx==0.21.0
 ifaddr==0.1.7
 jinja2==3.0.3
 PyJWT==2.1.0
diff --git a/requirements_test.txt b/requirements_test.txt
index 36cb9785ef6..7f7e36ac8d9 100644
--- a/requirements_test.txt
+++ b/requirements_test.txt
@@ -28,7 +28,7 @@ pytest-xdist==2.4.0
 pytest==6.2.5
 requests_mock==1.9.2
 responses==0.12.0
-respx==0.17.0
+respx==0.19.0
 stdlib-list==0.7.0
 tqdm==4.49.0
 types-atomicwrites==1.4.1
diff --git a/setup.py b/setup.py
index e08fbdf43e5..af23dc52159 100755
--- a/setup.py
+++ b/setup.py
@@ -42,7 +42,7 @@ REQUIRES = [
     "bcrypt==3.1.7",
     "certifi>=2021.5.30",
     "ciso8601==2.2.0",
-    "httpx==0.19.0",
+    "httpx==0.21.0",
     "ifaddr==0.1.7",
     "jinja2==3.0.3",
     "PyJWT==2.1.0",