diff --git a/homeassistant/components/youtube/__init__.py b/homeassistant/components/youtube/__init__.py
index c62c533be06..46c3b0d1902 100644
--- a/homeassistant/components/youtube/__init__.py
+++ b/homeassistant/components/youtube/__init__.py
@@ -11,6 +11,7 @@ from homeassistant.helpers.config_entry_oauth2_flow import (
     OAuth2Session,
     async_get_config_entry_implementation,
 )
+import homeassistant.helpers.device_registry as dr
 
 from .api import AsyncConfigEntryAuth
 from .const import AUTH, COORDINATOR, DOMAIN
@@ -37,11 +38,14 @@ async def async_setup_entry(hass: HomeAssistant, entry: ConfigEntry) -> bool:
     coordinator = YouTubeDataUpdateCoordinator(hass, auth)
 
     await coordinator.async_config_entry_first_refresh()
+
+    await delete_devices(hass, entry, coordinator)
+
     hass.data.setdefault(DOMAIN, {})[entry.entry_id] = {
         COORDINATOR: coordinator,
         AUTH: auth,
     }
-    await hass.config_entries.async_forward_entry_setups(entry, list(PLATFORMS))
+    await hass.config_entries.async_forward_entry_setups(entry, PLATFORMS)
 
     return True
 
@@ -52,3 +56,17 @@ async def async_unload_entry(hass: HomeAssistant, entry: ConfigEntry) -> bool:
     if unload_ok := await hass.config_entries.async_unload_platforms(entry, PLATFORMS):
         hass.data[DOMAIN].pop(entry.entry_id)
     return unload_ok
+
+
+async def delete_devices(
+    hass: HomeAssistant, entry: ConfigEntry, coordinator: YouTubeDataUpdateCoordinator
+) -> None:
+    """Delete all devices created by integration."""
+    channel_ids = list(coordinator.data)
+    device_registry = dr.async_get(hass)
+    dev_entries = dr.async_entries_for_config_entry(device_registry, entry.entry_id)
+    for dev_entry in dev_entries:
+        if any(identifier[1] in channel_ids for identifier in dev_entry.identifiers):
+            device_registry.async_update_device(
+                dev_entry.id, remove_config_entry_id=entry.entry_id
+            )