diff --git a/homeassistant/components/ipp/config_flow.py b/homeassistant/components/ipp/config_flow.py
index 3128583f218..ba12d7ec8e2 100644
--- a/homeassistant/components/ipp/config_flow.py
+++ b/homeassistant/components/ipp/config_flow.py
@@ -85,12 +85,12 @@ class IPPFlowHandler(ConfigFlow, domain=DOMAIN):
 
         unique_id = user_input[CONF_UUID] = info[CONF_UUID]
 
-        if unique_id is None and info[CONF_SERIAL] is not None:
+        if not unique_id and info[CONF_SERIAL]:
             _LOGGER.debug(
                 "Printer UUID is missing from IPP response. Falling back to IPP serial number"
             )
             unique_id = info[CONF_SERIAL]
-        elif unique_id is None:
+        elif not unique_id:
             _LOGGER.debug("Unable to determine unique id from IPP response")
 
         await self.async_set_unique_id(unique_id)
@@ -138,17 +138,17 @@ class IPPFlowHandler(ConfigFlow, domain=DOMAIN):
             return self.async_abort(reason="ipp_error")
 
         unique_id = self.discovery_info[CONF_UUID]
-        if unique_id is None and info[CONF_UUID] is not None:
+        if not unique_id and info[CONF_UUID]:
             _LOGGER.debug(
                 "Printer UUID is missing from discovery info. Falling back to IPP UUID"
             )
             unique_id = self.discovery_info[CONF_UUID] = info[CONF_UUID]
-        elif unique_id is None and info[CONF_SERIAL] is not None:
+        elif not unique_id and info[CONF_SERIAL]:
             _LOGGER.debug(
                 "Printer UUID is missing from discovery info and IPP response. Falling back to IPP serial number"
             )
             unique_id = info[CONF_SERIAL]
-        elif unique_id is None:
+        elif not unique_id:
             _LOGGER.debug(
                 "Unable to determine unique id from discovery info and IPP response"
             )
diff --git a/tests/components/ipp/test_config_flow.py b/tests/components/ipp/test_config_flow.py
index 0093ba57e5b..a468115f239 100644
--- a/tests/components/ipp/test_config_flow.py
+++ b/tests/components/ipp/test_config_flow.py
@@ -264,6 +264,24 @@ async def test_zeroconf_with_uuid_device_exists_abort(
     assert result["reason"] == "already_configured"
 
 
+async def test_zeroconf_empty_unique_id_required_abort(
+    hass: HomeAssistant, aioclient_mock: AiohttpClientMocker
+) -> None:
+    """Test we abort zeroconf flow if printer lacks (empty) unique identification."""
+    mock_connection(aioclient_mock, no_unique_id=True)
+
+    discovery_info = {
+        **MOCK_ZEROCONF_IPP_SERVICE_INFO,
+        "properties": {**MOCK_ZEROCONF_IPP_SERVICE_INFO["properties"], "UUID": ""},
+    }
+    result = await hass.config_entries.flow.async_init(
+        DOMAIN, context={"source": SOURCE_ZEROCONF}, data=discovery_info,
+    )
+
+    assert result["type"] == RESULT_TYPE_ABORT
+    assert result["reason"] == "unique_id_required"
+
+
 async def test_zeroconf_unique_id_required_abort(
     hass: HomeAssistant, aioclient_mock: AiohttpClientMocker
 ) -> None: