diff --git a/homeassistant/auth/__init__.py b/homeassistant/auth/__init__.py
index d2ce63f9490..e36eb6800fa 100644
--- a/homeassistant/auth/__init__.py
+++ b/homeassistant/auth/__init__.py
@@ -284,6 +284,7 @@ class AuthManager:
         self,
         user: models.User,
         name: Optional[str] = None,
+        is_active: Optional[bool] = None,
         group_ids: Optional[List[str]] = None,
     ) -> None:
         """Update a user."""
@@ -294,6 +295,12 @@ class AuthManager:
             kwargs["group_ids"] = group_ids
         await self._store.async_update_user(user, **kwargs)
 
+        if is_active is not None:
+            if is_active is True:
+                await self.async_activate_user(user)
+            else:
+                await self.async_deactivate_user(user)
+
     async def async_activate_user(self, user: models.User) -> None:
         """Activate a user."""
         await self._store.async_activate_user(user)
diff --git a/homeassistant/components/config/auth.py b/homeassistant/components/config/auth.py
index 440ac05cef4..c1d43a5d4a9 100644
--- a/homeassistant/components/config/auth.py
+++ b/homeassistant/components/config/auth.py
@@ -86,6 +86,7 @@ async def websocket_create(hass, connection, msg):
         vol.Required("type"): "config/auth/update",
         vol.Required("user_id"): str,
         vol.Optional("name"): str,
+        vol.Optional("is_active"): bool,
         vol.Optional("group_ids"): [str],
     }
 )
@@ -111,6 +112,16 @@ async def websocket_update(hass, connection, msg):
         )
         return
 
+    if user.is_owner and msg["is_active"] is False:
+        connection.send_message(
+            websocket_api.error_message(
+                msg["id"],
+                "cannot_deactivate_owner",
+                "Unable to deactivate owner.",
+            )
+        )
+        return
+
     msg.pop("type")
     msg_id = msg.pop("id")
 
diff --git a/tests/components/config/test_auth.py b/tests/components/config/test_auth.py
index e7e3c67e5d8..2d3cfe54f5a 100644
--- a/tests/components/config/test_auth.py
+++ b/tests/components/config/test_auth.py
@@ -285,3 +285,76 @@ async def test_update_system_generated(hass, hass_ws_client):
     assert not result["success"], result
     assert result["error"]["code"] == "cannot_modify_system_generated"
     assert user.name == "Test user"
+
+
+async def test_deactivate(hass, hass_ws_client):
+    """Test deactivation and reactivation of regular user."""
+    client = await hass_ws_client(hass)
+
+    user = await hass.auth.async_create_user("Test user")
+    assert user.is_active is True
+
+    await client.send_json(
+        {
+            "id": 5,
+            "type": "config/auth/update",
+            "user_id": user.id,
+            "name": "Updated name",
+            "is_active": False,
+        }
+    )
+
+    result = await client.receive_json()
+    assert result["success"], result
+    data_user = result["result"]["user"]
+    assert data_user["is_active"] is False
+
+    await client.send_json(
+        {
+            "id": 6,
+            "type": "config/auth/update",
+            "user_id": user.id,
+            "name": "Updated name",
+            "is_active": True,
+        }
+    )
+
+    result = await client.receive_json()
+    assert result["success"], result
+    data_user = result["result"]["user"]
+    assert data_user["is_active"] is True
+
+
+async def test_deactivate_owner(hass, hass_ws_client):
+    """Test that owner cannot be deactivated."""
+    user = MockUser(id="abc", name="Test Owner", is_owner=True).add_to_hass(hass)
+
+    assert user.is_active is True
+    assert user.is_owner is True
+
+    client = await hass_ws_client(hass)
+    await client.send_json(
+        {"id": 5, "type": "config/auth/update", "user_id": user.id, "is_active": False}
+    )
+
+    result = await client.receive_json()
+    assert not result["success"], result
+    assert result["error"]["code"] == "cannot_deactivate_owner"
+
+
+async def test_deactivate_system_generated(hass, hass_ws_client):
+    """Test that owner cannot be deactivated."""
+    client = await hass_ws_client(hass)
+
+    user = await hass.auth.async_create_system_user("Test user")
+    assert user.is_active is True
+    assert user.system_generated is True
+    assert user.is_owner is False
+
+    await client.send_json(
+        {"id": 5, "type": "config/auth/update", "user_id": user.id, "is_active": False}
+    )
+
+    result = await client.receive_json()
+    assert not result["success"], result
+    assert result["error"]["code"] == "cannot_modify_system_generated"