diff --git a/homeassistant/components/bluetooth/__init__.py b/homeassistant/components/bluetooth/__init__.py
index 5e96e5e336f..ef89bef7ca1 100644
--- a/homeassistant/components/bluetooth/__init__.py
+++ b/homeassistant/components/bluetooth/__init__.py
@@ -66,6 +66,7 @@ from .api import (
     async_rediscover_address,
     async_register_callback,
     async_register_scanner,
+    async_remove_scanner,
     async_scanner_by_source,
     async_scanner_count,
     async_scanner_devices_by_address,
@@ -109,6 +110,7 @@ __all__ = [
     "async_scanner_count",
     "async_scanner_devices_by_address",
     "async_get_advertisement_callback",
+    "async_remove_scanner",
     "BaseHaScanner",
     "HomeAssistantRemoteScanner",
     "BluetoothCallbackMatcher",
diff --git a/homeassistant/components/bluetooth/api.py b/homeassistant/components/bluetooth/api.py
index 505651edafd..9fd16ef1f43 100644
--- a/homeassistant/components/bluetooth/api.py
+++ b/homeassistant/components/bluetooth/api.py
@@ -183,6 +183,12 @@ def async_register_scanner(
     return _get_manager(hass).async_register_scanner(scanner, connection_slots)
 
 
+@hass_callback
+def async_remove_scanner(hass: HomeAssistant, source: str) -> None:
+    """Permanently remove a BleakScanner by source address."""
+    return _get_manager(hass).async_remove_scanner(source)
+
+
 @hass_callback
 def async_get_advertisement_callback(
     hass: HomeAssistant,
diff --git a/homeassistant/components/bluetooth/manager.py b/homeassistant/components/bluetooth/manager.py
index e192423484c..7ec5427af2b 100644
--- a/homeassistant/components/bluetooth/manager.py
+++ b/homeassistant/components/bluetooth/manager.py
@@ -253,6 +253,11 @@ class HomeAssistantBluetoothManager(BluetoothManager):
         unregister = super().async_register_scanner(scanner, connection_slots)
         return partial(self._async_unregister_scanner, scanner, unregister)
 
+    @hass_callback
+    def async_remove_scanner(self, source: str) -> None:
+        """Remove a scanner."""
+        self.storage.async_remove_advertisement_history(source)
+
     @hass_callback
     def _handle_config_entry_removed(
         self,
diff --git a/homeassistant/components/bluetooth/storage.py b/homeassistant/components/bluetooth/storage.py
index 6b4c7695fd2..369db4a7760 100644
--- a/homeassistant/components/bluetooth/storage.py
+++ b/homeassistant/components/bluetooth/storage.py
@@ -38,6 +38,12 @@ class BluetoothStorage:
         """Get all scanners."""
         return list(self._data.keys())
 
+    @callback
+    def async_remove_advertisement_history(self, scanner: str) -> None:
+        """Remove discovered devices by scanner."""
+        if self._data.pop(scanner, None):
+            self._store.async_delay_save(self._async_get_data, SCANNER_SAVE_DELAY)
+
     @callback
     def async_get_advertisement_history(
         self, scanner: str
diff --git a/tests/components/bluetooth/conftest.py b/tests/components/bluetooth/conftest.py
index 71ed155cbc7..1be39bfaa94 100644
--- a/tests/components/bluetooth/conftest.py
+++ b/tests/components/bluetooth/conftest.py
@@ -319,6 +319,7 @@ def register_hci0_scanner(hass: HomeAssistant) -> Generator[None]:
     cancel = bluetooth.async_register_scanner(hass, hci0_scanner)
     yield
     cancel()
+    bluetooth.async_remove_scanner(hass, hci0_scanner.source)
 
 
 @pytest.fixture
@@ -328,3 +329,4 @@ def register_hci1_scanner(hass: HomeAssistant) -> Generator[None]:
     cancel = bluetooth.async_register_scanner(hass, hci1_scanner)
     yield
     cancel()
+    bluetooth.async_remove_scanner(hass, hci1_scanner.source)
diff --git a/tests/components/bluetooth/test_init.py b/tests/components/bluetooth/test_init.py
index ba8792a79a3..9ad2c0e6caa 100644
--- a/tests/components/bluetooth/test_init.py
+++ b/tests/components/bluetooth/test_init.py
@@ -30,6 +30,7 @@ from homeassistant.components.bluetooth.const import (
     SOURCE_LOCAL,
     UNAVAILABLE_TRACK_SECONDS,
 )
+from homeassistant.components.bluetooth.manager import HomeAssistantBluetoothManager
 from homeassistant.components.bluetooth.match import (
     ADDRESS,
     CONNECTABLE,
@@ -3022,6 +3023,23 @@ async def test_scanner_count_connectable(hass: HomeAssistant) -> None:
     cancel()
 
 
+@pytest.mark.usefixtures("enable_bluetooth")
+async def test_scanner_remove(hass: HomeAssistant) -> None:
+    """Test permanently removing a scanner."""
+    scanner = FakeScanner("any", "any")
+    cancel = bluetooth.async_register_scanner(hass, scanner)
+    assert bluetooth.async_scanner_count(hass, connectable=True) == 1
+    device = generate_ble_device("44:44:33:11:23:45", "name")
+    adv = generate_advertisement_data(local_name="name", service_uuids=[])
+    inject_advertisement_with_time_and_source_connectable(
+        hass, device, adv, time.monotonic(), scanner.source, True
+    )
+    cancel()
+    bluetooth.async_remove_scanner(hass, scanner.source)
+    manager: HomeAssistantBluetoothManager = _get_manager()
+    assert not manager.storage.async_get_advertisement_history(scanner.source)
+
+
 @pytest.mark.usefixtures("enable_bluetooth")
 async def test_scanner_count(hass: HomeAssistant) -> None:
     """Test getting the connectable and non-connectable scanner count."""