diff --git a/homeassistant/components/uptime_kuma/__init__.py b/homeassistant/components/uptime_kuma/__init__.py
index 68234077976..4efe6a68193 100644
--- a/homeassistant/components/uptime_kuma/__init__.py
+++ b/homeassistant/components/uptime_kuma/__init__.py
@@ -6,7 +6,7 @@ from pythonkuma.update import UpdateChecker
 
 from homeassistant.const import Platform
 from homeassistant.core import HomeAssistant
-from homeassistant.helpers import config_validation as cv
+from homeassistant.helpers import config_validation as cv, device_registry as dr
 from homeassistant.helpers.aiohttp_client import async_get_clientsession
 from homeassistant.util.hass_dict import HassKey
 
@@ -43,6 +43,28 @@ async def async_setup_entry(hass: HomeAssistant, entry: UptimeKumaConfigEntry) -
     return True
 
 
+async def async_remove_config_entry_device(
+    hass: HomeAssistant,
+    config_entry: UptimeKumaConfigEntry,
+    device_entry: dr.DeviceEntry,
+) -> bool:
+    """Remove a stale device from a config entry."""
+
+    def normalize_key(id: str) -> int | str:
+        key = id.removeprefix(f"{config_entry.entry_id}_")
+        return int(key) if key.isnumeric() else key
+
+    return not any(
+        identifier
+        for identifier in device_entry.identifiers
+        if identifier[0] == DOMAIN
+        and (
+            identifier[1] == config_entry.entry_id
+            or normalize_key(identifier[1]) in config_entry.runtime_data.data
+        )
+    )
+
+
 async def async_unload_entry(hass: HomeAssistant, entry: UptimeKumaConfigEntry) -> bool:
     """Unload a config entry."""
     unload_ok = await hass.config_entries.async_unload_platforms(entry, _PLATFORMS)
diff --git a/tests/components/uptime_kuma/test_init.py b/tests/components/uptime_kuma/test_init.py
index 6e2ef43b14d..61d196f0263 100644
--- a/tests/components/uptime_kuma/test_init.py
+++ b/tests/components/uptime_kuma/test_init.py
@@ -8,8 +8,11 @@ from pythonkuma import UptimeKumaAuthenticationException, UptimeKumaException
 from homeassistant.components.uptime_kuma.const import DOMAIN
 from homeassistant.config_entries import SOURCE_REAUTH, ConfigEntryState
 from homeassistant.core import HomeAssistant
+from homeassistant.helpers import device_registry as dr
+from homeassistant.setup import async_setup_component
 
 from tests.common import MockConfigEntry
+from tests.typing import WebSocketGenerator
 
 
 @pytest.mark.usefixtures("mock_pythonkuma")
@@ -77,3 +80,85 @@ async def test_config_reauth_flow(
     assert "context" in flow
     assert flow["context"].get("source") == SOURCE_REAUTH
     assert flow["context"].get("entry_id") == config_entry.entry_id
+
+
+@pytest.mark.usefixtures("mock_pythonkuma")
+async def test_remove_stale_device(
+    hass: HomeAssistant,
+    config_entry: MockConfigEntry,
+    device_registry: dr.DeviceRegistry,
+    hass_ws_client: WebSocketGenerator,
+) -> None:
+    """Test we can remove a device that is not in the coordinator data."""
+    assert await async_setup_component(hass, "config", {})
+    ws_client = await hass_ws_client(hass)
+
+    config_entry.add_to_hass(hass)
+    await hass.config_entries.async_setup(config_entry.entry_id)
+    await hass.async_block_till_done()
+
+    assert config_entry.state is ConfigEntryState.LOADED
+
+    device_entry = device_registry.async_get_device(
+        identifiers={(DOMAIN, "123456789_1")}
+    )
+
+    config_entry.runtime_data.data.pop(1)
+    response = await ws_client.remove_device(device_entry.id, config_entry.entry_id)
+
+    assert response["success"]
+    assert (
+        device_registry.async_get_device(identifiers={(DOMAIN, "123456789_1")}) is None
+    )
+
+
+@pytest.mark.usefixtures("mock_pythonkuma")
+async def test_remove_current_device(
+    hass: HomeAssistant,
+    config_entry: MockConfigEntry,
+    device_registry: dr.DeviceRegistry,
+    hass_ws_client: WebSocketGenerator,
+) -> None:
+    """Test we cannot remove a device if it is still active."""
+    assert await async_setup_component(hass, "config", {})
+    ws_client = await hass_ws_client(hass)
+
+    config_entry.add_to_hass(hass)
+    await hass.config_entries.async_setup(config_entry.entry_id)
+    await hass.async_block_till_done()
+
+    assert config_entry.state is ConfigEntryState.LOADED
+
+    device_entry = device_registry.async_get_device(
+        identifiers={(DOMAIN, "123456789_1")}
+    )
+
+    response = await ws_client.remove_device(device_entry.id, config_entry.entry_id)
+
+    assert response["success"] is False
+    assert device_registry.async_get_device(identifiers={(DOMAIN, "123456789_1")})
+
+
+@pytest.mark.usefixtures("mock_pythonkuma")
+async def test_remove_entry_device(
+    hass: HomeAssistant,
+    config_entry: MockConfigEntry,
+    device_registry: dr.DeviceRegistry,
+    hass_ws_client: WebSocketGenerator,
+) -> None:
+    """Test we cannot remove the device with the update entity."""
+    assert await async_setup_component(hass, "config", {})
+    ws_client = await hass_ws_client(hass)
+
+    config_entry.add_to_hass(hass)
+    await hass.config_entries.async_setup(config_entry.entry_id)
+    await hass.async_block_till_done()
+
+    assert config_entry.state is ConfigEntryState.LOADED
+
+    device_entry = device_registry.async_get_device(identifiers={(DOMAIN, "123456789")})
+
+    response = await ws_client.remove_device(device_entry.id, config_entry.entry_id)
+
+    assert response["success"] is False
+    assert device_registry.async_get_device(identifiers={(DOMAIN, "123456789")})