diff --git a/homeassistant/package_constraints.txt b/homeassistant/package_constraints.txt
index 7cd0a56c337..7cd961c5da5 100644
--- a/homeassistant/package_constraints.txt
+++ b/homeassistant/package_constraints.txt
@@ -88,9 +88,9 @@ httplib2>=0.19.0
 # gRPC is an implicit dependency that we want to make explicit so we manage
 # upgrades intentionally. It is a large package to build from source and we
 # want to ensure we have wheels built.
-grpcio==1.71.0
-grpcio-status==1.71.0
-grpcio-reflection==1.71.0
+grpcio==1.72.0
+grpcio-status==1.72.0
+grpcio-reflection==1.72.0
 
 # This is a old unmaintained library and is replaced with pycryptodome
 pycrypto==1000000000.0.0
@@ -145,7 +145,7 @@ iso4217!=1.10.20220401
 
 # protobuf must be in package constraints for the wheel
 # builder to build binary wheels
-protobuf==5.29.2
+protobuf==6.30.2
 
 # faust-cchardet: Ensure we have a version we can build wheels
 # 2.1.18 is the first version that works with our wheel builder
diff --git a/script/gen_requirements_all.py b/script/gen_requirements_all.py
index f2e423536e8..87f7edaa892 100755
--- a/script/gen_requirements_all.py
+++ b/script/gen_requirements_all.py
@@ -117,9 +117,9 @@ httplib2>=0.19.0
 # gRPC is an implicit dependency that we want to make explicit so we manage
 # upgrades intentionally. It is a large package to build from source and we
 # want to ensure we have wheels built.
-grpcio==1.71.0
-grpcio-status==1.71.0
-grpcio-reflection==1.71.0
+grpcio==1.72.0
+grpcio-status==1.72.0
+grpcio-reflection==1.72.0
 
 # This is a old unmaintained library and is replaced with pycryptodome
 pycrypto==1000000000.0.0
@@ -174,7 +174,7 @@ iso4217!=1.10.20220401
 
 # protobuf must be in package constraints for the wheel
 # builder to build binary wheels
-protobuf==5.29.2
+protobuf==6.30.2
 
 # faust-cchardet: Ensure we have a version we can build wheels
 # 2.1.18 is the first version that works with our wheel builder