diff --git a/homeassistant/components/cloud/manifest.json b/homeassistant/components/cloud/manifest.json
index 02ffa0a4775..3a6d942f5ea 100644
--- a/homeassistant/components/cloud/manifest.json
+++ b/homeassistant/components/cloud/manifest.json
@@ -2,7 +2,7 @@
   "domain": "cloud",
   "name": "Home Assistant Cloud",
   "documentation": "https://www.home-assistant.io/integrations/cloud",
-  "requirements": ["hass-nabucasa==0.55.0"],
+  "requirements": ["hass-nabucasa==0.56.0"],
   "dependencies": ["http", "webhook"],
   "after_dependencies": ["google_assistant", "alexa"],
   "codeowners": ["@home-assistant/cloud"],
diff --git a/homeassistant/package_constraints.txt b/homeassistant/package_constraints.txt
index 4198b4ee62b..b285f568824 100644
--- a/homeassistant/package_constraints.txt
+++ b/homeassistant/package_constraints.txt
@@ -16,10 +16,10 @@ bluetooth-adapters==0.5.1
 bluetooth-auto-recovery==0.3.3
 certifi>=2021.5.30
 ciso8601==2.2.0
-cryptography==37.0.4
+cryptography==38.0.1
 dbus-fast==1.13.0
 fnvhash==0.1.0
-hass-nabucasa==0.55.0
+hass-nabucasa==0.56.0
 home-assistant-bluetooth==1.3.0
 home-assistant-frontend==20220907.2
 httpx==0.23.0
@@ -132,6 +132,3 @@ iso4217!=1.10.20220401
 
 # Pandas 1.4.4 has issues with wheels om armhf + Py3.10
 pandas==1.4.3
-
-# pyopenssl 22.1.0 requires pycryptography > 38 and we have 37
-pyopenssl==22.0.0
diff --git a/pyproject.toml b/pyproject.toml
index 8381098badd..c76b015c84a 100644
--- a/pyproject.toml
+++ b/pyproject.toml
@@ -42,7 +42,7 @@ dependencies    = [
     "lru-dict==1.1.8",
     "PyJWT==2.5.0",
     # PyJWT has loose dependency. We want the latest one.
-    "cryptography==37.0.4",
+    "cryptography==38.0.1",
     "orjson==3.7.11",
     "pip>=21.0,<22.3",
     "python-slugify==4.0.1",
diff --git a/requirements.txt b/requirements.txt
index 2f36b947bca..28d3c11081b 100644
--- a/requirements.txt
+++ b/requirements.txt
@@ -16,7 +16,7 @@ ifaddr==0.1.7
 jinja2==3.1.2
 lru-dict==1.1.8
 PyJWT==2.5.0
-cryptography==37.0.4
+cryptography==38.0.1
 orjson==3.7.11
 pip>=21.0,<22.3
 python-slugify==4.0.1
diff --git a/requirements_all.txt b/requirements_all.txt
index ffed2fdba6f..894ca325b44 100644
--- a/requirements_all.txt
+++ b/requirements_all.txt
@@ -829,7 +829,7 @@ habitipy==0.2.0
 hangups==0.4.18
 
 # homeassistant.components.cloud
-hass-nabucasa==0.55.0
+hass-nabucasa==0.56.0
 
 # homeassistant.components.splunk
 hass_splunk==0.1.1
diff --git a/requirements_test_all.txt b/requirements_test_all.txt
index 1b268270ff0..9d771174d23 100644
--- a/requirements_test_all.txt
+++ b/requirements_test_all.txt
@@ -615,7 +615,7 @@ habitipy==0.2.0
 hangups==0.4.18
 
 # homeassistant.components.cloud
-hass-nabucasa==0.55.0
+hass-nabucasa==0.56.0
 
 # homeassistant.components.tasmota
 hatasmota==0.6.1
diff --git a/script/gen_requirements_all.py b/script/gen_requirements_all.py
index eec89d4210c..d0eb830f088 100755
--- a/script/gen_requirements_all.py
+++ b/script/gen_requirements_all.py
@@ -142,9 +142,6 @@ iso4217!=1.10.20220401
 
 # Pandas 1.4.4 has issues with wheels om armhf + Py3.10
 pandas==1.4.3
-
-# pyopenssl 22.1.0 requires pycryptography > 38 and we have 37
-pyopenssl==22.0.0
 """
 
 IGNORE_PRE_COMMIT_HOOK_ID = (