diff --git a/homeassistant/components/tile/__init__.py b/homeassistant/components/tile/__init__.py
index 91e1567cd65..2f00dabbcb6 100644
--- a/homeassistant/components/tile/__init__.py
+++ b/homeassistant/components/tile/__init__.py
@@ -7,7 +7,7 @@ from pytile.errors import InvalidAuthError, SessionExpiredError, TileError
 
 from homeassistant.const import CONF_PASSWORD, CONF_USERNAME
 from homeassistant.exceptions import ConfigEntryNotReady
-from homeassistant.helpers import aiohttp_client
+from homeassistant.helpers import aiohttp_client, entity_registry
 from homeassistant.helpers.update_coordinator import DataUpdateCoordinator, UpdateFailed
 from homeassistant.util.async_ import gather_with_concurrency
 
@@ -33,6 +33,31 @@ async def async_setup_entry(hass, entry):
     hass.data[DOMAIN][DATA_COORDINATOR][entry.entry_id] = {}
     hass.data[DOMAIN][DATA_TILE][entry.entry_id] = {}
 
+    # The existence of shared Tiles across multiple accounts requires an entity ID
+    # change:
+    #
+    # Old: tile_{uuid}
+    # New: {username}_{uuid}
+    #
+    # Find any entities with the old format and update them:
+    ent_reg = entity_registry.async_get(hass)
+    for entity in [
+        e
+        for e in ent_reg.entities.values()
+        if e.config_entry_id == entry.entry_id
+        and not e.unique_id.startswith(entry.data[CONF_USERNAME])
+    ]:
+        new_unique_id = f"{entry.data[CONF_USERNAME]}_".join(
+            entity.unique_id.split(f"{DOMAIN}_")
+        )
+        LOGGER.debug(
+            "Migrating entity %s from old unique ID '%s' to new unique ID '%s'",
+            entity.entity_id,
+            entity.unique_id,
+            new_unique_id,
+        )
+        ent_reg.async_update_entity(entity.entity_id, new_unique_id=new_unique_id)
+
     websession = aiohttp_client.async_get_clientsession(hass)
 
     try:
diff --git a/homeassistant/components/tile/device_tracker.py b/homeassistant/components/tile/device_tracker.py
index 7571e235ef1..add6e5f94a0 100644
--- a/homeassistant/components/tile/device_tracker.py
+++ b/homeassistant/components/tile/device_tracker.py
@@ -30,7 +30,9 @@ async def async_setup_entry(hass, entry, async_add_entities):
     async_add_entities(
         [
             TileDeviceTracker(
-                hass.data[DOMAIN][DATA_COORDINATOR][entry.entry_id][tile_uuid], tile
+                entry,
+                hass.data[DOMAIN][DATA_COORDINATOR][entry.entry_id][tile_uuid],
+                tile,
             )
             for tile_uuid, tile in hass.data[DOMAIN][DATA_TILE][entry.entry_id].items()
         ]
@@ -61,10 +63,11 @@ async def async_setup_scanner(hass, config, async_see, discovery_info=None):
 class TileDeviceTracker(CoordinatorEntity, TrackerEntity):
     """Representation of a network infrastructure device."""
 
-    def __init__(self, coordinator, tile):
+    def __init__(self, entry, coordinator, tile):
         """Initialize."""
         super().__init__(coordinator)
         self._attrs = {ATTR_ATTRIBUTION: DEFAULT_ATTRIBUTION}
+        self._entry = entry
         self._tile = tile
 
     @property
@@ -116,7 +119,7 @@ class TileDeviceTracker(CoordinatorEntity, TrackerEntity):
     @property
     def unique_id(self):
         """Return the unique ID of the entity."""
-        return f"tile_{self._tile.uuid}"
+        return f"{self._entry.data[CONF_USERNAME]}_{self._tile.uuid}"
 
     @property
     def source_type(self):
diff --git a/homeassistant/components/tile/manifest.json b/homeassistant/components/tile/manifest.json
index a17c099509e..e8d386f4a88 100644
--- a/homeassistant/components/tile/manifest.json
+++ b/homeassistant/components/tile/manifest.json
@@ -3,7 +3,7 @@
   "name": "Tile",
   "config_flow": true,
   "documentation": "https://www.home-assistant.io/integrations/tile",
-  "requirements": ["pytile==5.2.0"],
+  "requirements": ["pytile==5.2.2"],
   "codeowners": ["@bachya"],
   "iot_class": "cloud_polling"
 }
diff --git a/requirements_all.txt b/requirements_all.txt
index ee617b75b74..8e422d67a16 100644
--- a/requirements_all.txt
+++ b/requirements_all.txt
@@ -1918,7 +1918,7 @@ python_opendata_transport==0.2.1
 pythonegardia==1.0.40
 
 # homeassistant.components.tile
-pytile==5.2.0
+pytile==5.2.2
 
 # homeassistant.components.touchline
 pytouchline==0.7
diff --git a/requirements_test_all.txt b/requirements_test_all.txt
index 3a46d378017..22efc23a38b 100644
--- a/requirements_test_all.txt
+++ b/requirements_test_all.txt
@@ -1061,7 +1061,7 @@ python-velbus==2.1.2
 python_awair==0.2.1
 
 # homeassistant.components.tile
-pytile==5.2.0
+pytile==5.2.2
 
 # homeassistant.components.traccar
 pytraccar==0.9.0