diff --git a/homeassistant/package_constraints.txt b/homeassistant/package_constraints.txt
index 617a057743b..6d22aa51b24 100644
--- a/homeassistant/package_constraints.txt
+++ b/homeassistant/package_constraints.txt
@@ -51,6 +51,11 @@ httplib2>=0.19.0
 # https://github.com/home-assistant/core/issues/40148
 grpcio==1.31.0
 
+# Newer versions of cloud pubsub pin a higher version of grpcio. This can
+# be reverted when the grpcio pin is reverted, see:
+# https://github.com/home-assistant/core/issues/53427
+google-cloud-pubsub==2.1.0
+
 # This is a old unmaintained library and is replaced with pycryptodome
 pycrypto==1000000000.0.0
 
diff --git a/script/gen_requirements_all.py b/script/gen_requirements_all.py
index 7dcc4f71fe8..934ea9be90c 100755
--- a/script/gen_requirements_all.py
+++ b/script/gen_requirements_all.py
@@ -73,6 +73,11 @@ httplib2>=0.19.0
 # https://github.com/home-assistant/core/issues/40148
 grpcio==1.31.0
 
+# Newer versions of cloud pubsub pin a higher version of grpcio. This can
+# be reverted when the grpcio pin is reverted, see:
+# https://github.com/home-assistant/core/issues/53427
+google-cloud-pubsub==2.1.0
+
 # This is a old unmaintained library and is replaced with pycryptodome
 pycrypto==1000000000.0.0