diff --git a/esphome/components/gpio/binary_sensor/__init__.py b/esphome/components/gpio/binary_sensor/__init__.py
index 59f54520fa..8372bc7e08 100644
--- a/esphome/components/gpio/binary_sensor/__init__.py
+++ b/esphome/components/gpio/binary_sensor/__init__.py
@@ -4,7 +4,13 @@ from esphome import pins
 import esphome.codegen as cg
 from esphome.components import binary_sensor
 import esphome.config_validation as cv
-from esphome.const import CONF_ID, CONF_NAME, CONF_NUMBER, CONF_PIN
+from esphome.const import (
+    CONF_ALLOW_OTHER_USES,
+    CONF_ID,
+    CONF_NAME,
+    CONF_NUMBER,
+    CONF_PIN,
+)
 from esphome.core import CORE
 
 from .. import gpio_ns
@@ -76,6 +82,18 @@ async def to_code(config):
         )
         use_interrupt = False
 
+    # Check if pin is shared with other components (allow_other_uses)
+    # When a pin is shared, interrupts can interfere with other components
+    # (e.g., duty_cycle sensor) that need to monitor the pin's state changes
+    if use_interrupt and config[CONF_PIN].get(CONF_ALLOW_OTHER_USES, False):
+        _LOGGER.info(
+            "GPIO binary_sensor '%s': Disabling interrupts because pin %s is shared with other components. "
+            "The sensor will use polling mode for compatibility with other pin uses.",
+            config.get(CONF_NAME, config[CONF_ID]),
+            config[CONF_PIN][CONF_NUMBER],
+        )
+        use_interrupt = False
+
     cg.add(var.set_use_interrupt(use_interrupt))
     if use_interrupt:
         cg.add(var.set_interrupt_type(config[CONF_INTERRUPT_TYPE]))