diff --git a/package/guile/guile.mk b/package/guile/guile.mk
index ca54a4d77f..88c74143bf 100644
--- a/package/guile/guile.mk
+++ b/package/guile/guile.mk
@@ -32,6 +32,11 @@ ifeq ($(BR2_STATIC_LIBS),y)
 GUILE_CFLAGS += -DGC_NO_DLOPEN
 endif
 
+# Triggers assembler error with -Os
+ifeq ($(BR2_TOOLCHAIN_EXTERNAL_CODESOURCERY_ARM)$(BR2_OPTIMIZE_S),yy)
+GUILE_CFLAGS += -O2
+endif
+
 # It can use readline, but on the condition that it was build against
 # ncurses. If both aren't present disable readline support since the
 # host readline/ncurses support can poison the build.