diff --git a/Makefile b/Makefile
index 188ce9adc7..d4faa021cd 100644
--- a/Makefile
+++ b/Makefile
@@ -709,6 +709,9 @@ endif
 		echo "PRETTY_NAME=\"Buildroot $(BR2_VERSION)\"" \
 	) >  $(TARGET_DIR)/etc/os-release
 
+	@$(call MESSAGE,"Sanitizing RPATH in target tree")
+	$(TOPDIR)/support/scripts/fix-rpath target
+
 	@$(foreach d, $(call qstrip,$(BR2_ROOTFS_OVERLAY)), \
 		$(call MESSAGE,"Copying overlay $(d)"); \
 		rsync -a --ignore-times --keep-dirlinks $(RSYNC_VCS_EXCLUSIONS) \