diff --git a/package/strace/Config.in b/package/strace/Config.in
index ad8d30816e..bc521e0036 100644
--- a/package/strace/Config.in
+++ b/package/strace/Config.in
@@ -1,6 +1,8 @@
 config BR2_PACKAGE_STRACE
 	bool "strace"
 	depends on !BR2_nios2
+	depends on !((BR2_mips || BR2_mipsel || BR2_mips64 || BR2_mips64el) \
+	             && BR2_TOOLCHAIN_USES_UCLIBC)
 	depends on BR2_LARGEFILE
 	help
 	  A useful diagnostic, instructional, and debugging tool.
@@ -11,3 +13,7 @@ config BR2_PACKAGE_STRACE
 
 comment "strace needs a toolchain w/ largefile"
 	depends on !BR2_LARGEFILE
+
+comment "strace is not supported on MIPS using a uClibc toolchain"
+	depends on (BR2_mips || BR2_mipsel || BR2_mips64 || BR2_mips64el) && \
+	           BR2_TOOLCHAIN_USES_UCLIBC