diff --git a/package/opus/opus.mk b/package/opus/opus.mk
index f746a2f828..71fdcb3f0c 100644
--- a/package/opus/opus.mk
+++ b/package/opus/opus.mk
@@ -14,4 +14,10 @@ ifeq ($(BR2_PACKAGE_OPUS_FIXED_POINT),y)
 OPUS_CONF_OPTS += --enable-fixed-point
 endif
 
+# When we're on ARM, but we don't have ARM instructions (only
+# Thumb-2), disable the usage of assembly as it is not Thumb-ready.
+ifeq ($(BR2_arm)$(BR2_armeb):$(BR2_ARM_CPU_HAS_ARM),y:)
+OPUS_CONF_OPTS += --disable-asm
+endif
+
 $(eval $(autotools-package))