diff --git a/supervisor/host/network.py b/supervisor/host/network.py
index dd6fdc47a..a3ddd78af 100644
--- a/supervisor/host/network.py
+++ b/supervisor/host/network.py
@@ -115,6 +115,9 @@ class NetworkManager(CoreSysAttributes):
 
             try:
                 await inet.settings.update(settings)
+                await self.sys_dbus.network.activate_connection(
+                    inet.settings.object_path, inet.object_path
+                )
             except DBusError as err:
                 _LOGGER.error("Can't update config on %s: %s", interface.name, err)
                 raise HostNetworkError() from err
diff --git a/tests/fixtures/org_freedesktop_NetworkManager-ActivateConnection.fixture b/tests/fixtures/org_freedesktop_NetworkManager-ActivateConnection.fixture
new file mode 100644
index 000000000..dd626a0f3
--- /dev/null
+++ b/tests/fixtures/org_freedesktop_NetworkManager-ActivateConnection.fixture
@@ -0,0 +1 @@
+()
\ No newline at end of file